Bioactive Bone Cement Based on CaO─SiO2─P2O5 Glass

A CaO─SiO2─P2O5─CaF2 glass powder hardened within 4 min when mixed with an ammonium phosphate solution to form CaNH4PO4·H2O. After it had soaked in a simulated body fluid for 3 d, forming hydroxyapatite, the cement showed a compressive strength of 80 MPa. Implanted into a rat tibia, the mixed paste...

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Veröffentlicht in:Journal of the American Ceramic Society 1991-07, Vol.74 (7), p.1739-1741
Hauptverfasser: Kokubo, Tadashi, Yoshihara, Satoru, Nishimura, Naomi, Yamamuro, Takao, Nakamura, Takashi
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container_end_page 1741
container_issue 7
container_start_page 1739
container_title Journal of the American Ceramic Society
container_volume 74
creator Kokubo, Tadashi
Yoshihara, Satoru
Nishimura, Naomi
Yamamuro, Takao
Nakamura, Takashi
description A CaO─SiO2─P2O5─CaF2 glass powder hardened within 4 min when mixed with an ammonium phosphate solution to form CaNH4PO4·H2O. After it had soaked in a simulated body fluid for 3 d, forming hydroxyapatite, the cement showed a compressive strength of 80 MPa. Implanted into a rat tibia, the mixed paste formed a tight chemical bond to the living bone within 4 weeks. Such a bioactive cement could be useful not only for fixing various kinds of implants to the surrounding bones but also, by itself, as a bone filler.
doi_str_mv 10.1111/j.1151-2916.1991.tb07176.x
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source Wiley Online Library Journals Frontfile Complete
subjects bioceramics
Biological and medical sciences
calcia
cements
hydroxyapatite
Medical sciences
silica
Traumas. Diseases due to physical agents
title Bioactive Bone Cement Based on CaO─SiO2─P2O5 Glass
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