Bioactive Bone Cement Based on CaO─SiO2─P2O5 Glass
A CaO─SiO2─P2O5─CaF2 glass powder hardened within 4 min when mixed with an ammonium phosphate solution to form CaNH4PO4·H2O. After it had soaked in a simulated body fluid for 3 d, forming hydroxyapatite, the cement showed a compressive strength of 80 MPa. Implanted into a rat tibia, the mixed paste...
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Veröffentlicht in: | Journal of the American Ceramic Society 1991-07, Vol.74 (7), p.1739-1741 |
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container_title | Journal of the American Ceramic Society |
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creator | Kokubo, Tadashi Yoshihara, Satoru Nishimura, Naomi Yamamuro, Takao Nakamura, Takashi |
description | A CaO─SiO2─P2O5─CaF2 glass powder hardened within 4 min when mixed with an ammonium phosphate solution to form CaNH4PO4·H2O. After it had soaked in a simulated body fluid for 3 d, forming hydroxyapatite, the cement showed a compressive strength of 80 MPa. Implanted into a rat tibia, the mixed paste formed a tight chemical bond to the living bone within 4 weeks. Such a bioactive cement could be useful not only for fixing various kinds of implants to the surrounding bones but also, by itself, as a bone filler. |
doi_str_mv | 10.1111/j.1151-2916.1991.tb07176.x |
format | Article |
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After it had soaked in a simulated body fluid for 3 d, forming hydroxyapatite, the cement showed a compressive strength of 80 MPa. Implanted into a rat tibia, the mixed paste formed a tight chemical bond to the living bone within 4 weeks. Such a bioactive cement could be useful not only for fixing various kinds of implants to the surrounding bones but also, by itself, as a bone filler.</description><identifier>ISSN: 0002-7820</identifier><identifier>EISSN: 1551-2916</identifier><identifier>DOI: 10.1111/j.1151-2916.1991.tb07176.x</identifier><identifier>CODEN: JACTAW</identifier><language>eng</language><publisher>Oxford, UK: Blackwell Publishing Ltd</publisher><subject>bioceramics ; Biological and medical sciences ; calcia ; cements ; hydroxyapatite ; Medical sciences ; silica ; Traumas. 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After it had soaked in a simulated body fluid for 3 d, forming hydroxyapatite, the cement showed a compressive strength of 80 MPa. Implanted into a rat tibia, the mixed paste formed a tight chemical bond to the living bone within 4 weeks. Such a bioactive cement could be useful not only for fixing various kinds of implants to the surrounding bones but also, by itself, as a bone filler.</description><subject>bioceramics</subject><subject>Biological and medical sciences</subject><subject>calcia</subject><subject>cements</subject><subject>hydroxyapatite</subject><subject>Medical sciences</subject><subject>silica</subject><subject>Traumas. 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Diseases due to physical agents</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Kokubo, Tadashi</creatorcontrib><creatorcontrib>Yoshihara, Satoru</creatorcontrib><creatorcontrib>Nishimura, Naomi</creatorcontrib><creatorcontrib>Yamamuro, Takao</creatorcontrib><creatorcontrib>Nakamura, Takashi</creatorcontrib><collection>Istex</collection><collection>Pascal-Francis</collection><jtitle>Journal of the American Ceramic Society</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Kokubo, Tadashi</au><au>Yoshihara, Satoru</au><au>Nishimura, Naomi</au><au>Yamamuro, Takao</au><au>Nakamura, Takashi</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Bioactive Bone Cement Based on CaO─SiO2─P2O5 Glass</atitle><jtitle>Journal of the American Ceramic Society</jtitle><date>1991-07</date><risdate>1991</risdate><volume>74</volume><issue>7</issue><spage>1739</spage><epage>1741</epage><pages>1739-1741</pages><issn>0002-7820</issn><eissn>1551-2916</eissn><coden>JACTAW</coden><abstract>A CaO─SiO2─P2O5─CaF2 glass powder hardened within 4 min when mixed with an ammonium phosphate solution to form CaNH4PO4·H2O. After it had soaked in a simulated body fluid for 3 d, forming hydroxyapatite, the cement showed a compressive strength of 80 MPa. Implanted into a rat tibia, the mixed paste formed a tight chemical bond to the living bone within 4 weeks. Such a bioactive cement could be useful not only for fixing various kinds of implants to the surrounding bones but also, by itself, as a bone filler.</abstract><cop>Oxford, UK</cop><pub>Blackwell Publishing Ltd</pub><doi>10.1111/j.1151-2916.1991.tb07176.x</doi><tpages>3</tpages></addata></record> |
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source | Wiley Online Library Journals Frontfile Complete |
subjects | bioceramics Biological and medical sciences calcia cements hydroxyapatite Medical sciences silica Traumas. Diseases due to physical agents |
title | Bioactive Bone Cement Based on CaO─SiO2─P2O5 Glass |
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