Bioactive Bone Cement Based on CaO─SiO2─P2O5 Glass

A CaO─SiO2─P2O5─CaF2 glass powder hardened within 4 min when mixed with an ammonium phosphate solution to form CaNH4PO4·H2O. After it had soaked in a simulated body fluid for 3 d, forming hydroxyapatite, the cement showed a compressive strength of 80 MPa. Implanted into a rat tibia, the mixed paste...

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Veröffentlicht in:	Journal of the American Ceramic Society 1991-07, Vol.74 (7), p.1739-1741
Hauptverfasser:	Kokubo, Tadashi, Yoshihara, Satoru, Nishimura, Naomi, Yamamuro, Takao, Nakamura, Takashi
Format:	Artikel
Sprache:	eng
Schlagworte:	bioceramics Biological and medical sciences calcia cements hydroxyapatite Medical sciences silica Traumas. Diseases due to physical agents
Online-Zugang:	Volltext
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Beschreibung
Zusammenfassung:	A CaO─SiO2─P2O5─CaF2 glass powder hardened within 4 min when mixed with an ammonium phosphate solution to form CaNH4PO4·H2O. After it had soaked in a simulated body fluid for 3 d, forming hydroxyapatite, the cement showed a compressive strength of 80 MPa. Implanted into a rat tibia, the mixed paste formed a tight chemical bond to the living bone within 4 weeks. Such a bioactive cement could be useful not only for fixing various kinds of implants to the surrounding bones but also, by itself, as a bone filler.
ISSN:	0002-7820 1551-2916
DOI:	10.1111/j.1151-2916.1991.tb07176.x