SPECTROPHOTOMETRIC DETERMINATION OF ATROPINE

SPECTROPHOTOMETRIC DETERMINATION OF ATROPINE

Atropine reacts with sodium nitrite and 1-naphthylamine to give an orange color having maximum absorbance at 460-470 nm. The reaction is specific for atropine, having 0.1 μg/10ml as visual limit of identification and provides a basis for a new spectrophotometric determination of pure atropine in uri...

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Veröffentlicht in:Analytical letters 1994-07, Vol.27 (10), p.1833-1845
Hauptverfasser: Aman, Tehseen, Hassan, Ahmad, Khokhar, Irshad, Rashid, A.
Format: Artikel
Sprache:eng
Schlagworte:
1-naphthylamine
Analysis
atropine
Biological and medical sciences
General pharmacology
Medical sciences
Pharmacology. Drug treatments
sodium nitrite
Spectrophotometer
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Zusammenfassung:Atropine reacts with sodium nitrite and 1-naphthylamine to give an orange color having maximum absorbance at 460-470 nm. The reaction is specific for atropine, having 0.1 μg/10ml as visual limit of identification and provides a basis for a new spectrophotometric determination of pure atropine in urine, from pharmaceutical preparations in minute quantities, and in the presence of other drugs. The maximum tolerable limits of these are reported.
ISSN:0003-2719
1532-236X
DOI:10.1080/00032719408002635