1α‐Hydroxyvitamin D3 inhibits Type II collagen‐induced arthritis in rats

The effects of 1α‐hydroxyvitamin D3 and 24,25‐dihydroxyvitamin D3 on Type II collagen‐induced arthritis in rats, an experimental model of rheumatoid arthritis, were examined. Oral administration of 1α‐hydroxyvitamin D3 significantly suppressed the incidence of arthritis and inhibited hind paw swelli...

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Veröffentlicht in:	FEBS letters 1994-01, Vol.337 (3), p.248-250
Hauptverfasser:	Tsuji, Michiko, Fujii, Katsuyuki, Nakano, Toshiaki, Nishii, Yasuho
Format:	Artikel
Sprache:	eng
Schlagworte:	1α,25-(OH)2-D3,1α,25-dihydroxyvitamin D3 1α-Hydroxy vitamin D3 1α-OH-D3, 1α-hydroxyvitamin D3 24,25-(OH)2-D3, 24,25-dihydroxyvitamin D3 Anti-Type II collagen antibody Biological and medical sciences Cell physiology CIA, collagen-induced arthritis Collagen-induced arthritis ELISA, enzyme-linked immunosorbent assay Fundamental and applied biological sciences. Psychology Molecular and cellular biology RA, rheumatoid arthritis Responses to growth factors, tumor promotors, other factors Rheumatoid arthritis
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