First-Derivative Spectrophotometric Assay of Timolol Maleate in Ophthalmic Solutions

This research reports the application of derivative spectrophotometry to the determination of timolol maleate in ophthalmic solutions. A systematic approach developed for optimisation of the derivative order, graphical measurements and instrumental conditions led to the adoption of first-order spect...

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Veröffentlicht in:	Analytical letters 1996-03, Vol.29 (5), p.755-762
Hauptverfasser:	Santoro, Maria Iněs R.M., Cho, Hyun Sun, Kedor-Hackmann, Erika R.M.
Format:	Artikel
Sprache:	eng
Schlagworte:	Analysis Biological and medical sciences first-order derivative spectrophotometry General pharmacology Medical sciences ophthalmic solutions Pharmacology. Drug treatments Timolol maleate
Online-Zugang:	Volltext
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Beschreibung
Zusammenfassung:	This research reports the application of derivative spectrophotometry to the determination of timolol maleate in ophthalmic solutions. A systematic approach developed for optimisation of the derivative order, graphical measurements and instrumental conditions led to the adoption of first-order spectrophotometry as a method with suitable precision and selectivity for the determination of timolol maleate in ophthalmic solutions without previous treatment.
ISSN:	0003-2719 1532-236X
DOI:	10.1080/00032719608001781