Reduced Vancomycin Susceptibility in an In Vitro Catheter-Related Biofilm Model Correlates with Poor Therapeutic Outcomes in Experimental Endocarditis Due to Methicillin-Resistant Staphylococcus aureus

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Veröffentlicht in:	Antimicrobial Agents and Chemotherapy 2013-03, Vol.57 (3), p.1447-1454
Hauptverfasser:	ABDELHADY, Wessam, BAYER, Arnold S, SEIDL, Kati, NAST, Cynthia C, KIEDROWSKI, Megan R, HORSWILL, Alexander R, YEAMAN, Michael R, XIONG, Yan Q
Format:	Artikel
Sprache:	eng
Schlagworte:	Anti-Bacterial Agents Anti-Bacterial Agents - metabolism Anti-Bacterial Agents - pharmacology Antibiotics Antibiotics. Antiinfectious agents. Antiparasitic agents Bacterial diseases Biofilms Biofilms - drug effects Biofilms - growth & development Biological and medical sciences Cardiology. Vascular system Cardiovascular system Catheter-Related Infections - complications Catheter-Related Infections - drug therapy Catheter-Related Infections - microbiology Catheters Cell Wall - chemistry Cell Wall - drug effects Cell walls Drug resistance Endocardial and cardiac valvular diseases Endocarditis Endocarditis, Bacterial - complications Endocarditis, Bacterial - drug therapy Endocarditis, Bacterial - microbiology Endopeptidase K Endopeptidase K - pharmacology Heart Human bacterial diseases Humans Infection Infectious diseases Mechanisms of Resistance Medical sciences Methicillin-Resistant Staphylococcus aureus Methicillin-Resistant Staphylococcus aureus - drug effects Methicillin-Resistant Staphylococcus aureus - growth & development Methicillin-Resistant Staphylococcus aureus - isolation & purification Microbial Sensitivity Tests Models, Biological Pharmacology. Drug treatments Sepsis Staphylococcal Infections - complications Staphylococcal Infections - drug therapy Staphylococcal Infections - microbiology Staphylococcal infections, streptococcal infections, pneumococcal infections Staphylococcus aureus Vancomycin Vancomycin - metabolism Vancomycin - pharmacology Vancomycin Resistance - drug effects
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Zusammenfassung:	Classifications Services AAC Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley Reddit StumbleUpon Twitter current issue AAC About AAC Subscribers Authors Reviewers Advertisers Inquiries from the Press Permissions & Commercial Reprints ASM Journals Public Access Policy AAC RSS Feeds 1752 N Street N.W. • Washington DC 20036 202.737.3600 • 202.942.9355 fax • journals@asmusa.org Print ISSN: 0066-4804 Online ISSN: 1098-6596 Copyright © 2014 by the American Society for Microbiology. For an alternate route to AAC .asm.org, visit: AAC
ISSN:	0066-4804 1098-6596
DOI:	10.1128/AAC.02073-12