Increasing Effect of an Oral Intake of L-Hydroxyproline on the Soluble Collagen Content of Skin and Collagen Fragments in Rat Serum

We examined the effects of oral L-hydroxyproline (Hyp) on collagen in the body. After 2 weeks' administration of Hyp (0.5 or 1 g/kg) to F344 male rats, the soluble collagen content of the skin had increased, and the serum concentration of collagen peptides was correlated with the skin content o...

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Veröffentlicht in:	Bioscience, biotechnology, and biochemistry biotechnology, and biochemistry, 2012, Vol.76 (6), p.1242-1244
Hauptverfasser:	AOKI, Mami, SUTO, Kouzou, KOMATSU, Miho, KAMIMURA, Ayako, MORISHITA, Koji, YAMASAKI, Motoo, TAKAO, Toshifumi
Format:	Artikel
Sprache:	eng
Schlagworte:	Administration, Oral Animals Biological and medical sciences collagen Collagen - metabolism Dose-Response Relationship, Drug Fundamental and applied biological sciences. Psychology Hydroxyproline - metabolism Hydroxyproline - pharmacology L-hydroxyproline Male oral intake Peptide Fragments - blood Rats Rats, Inbred F344 Skin - drug effects Skin - metabolism Solubility
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