Abscess formation in Listeria monocytogenes-infected γδT cell deficient mouse mutants involves αβT cells
Although mutant mice lacking γδT cells resolve Listeria monocytogenesinfection, extensive abscesses are formed. Manifestation of these inflammatory lesions is prevented by in vivodepletion with monoclonal antibodies of CD4, CD8 or both T cell subsets. We conclude that these inflammatory tissue react...
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Veröffentlicht in: | Microbial pathogenesis 1997, Vol.22 (2), p.123-128 |
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container_issue | 2 |
container_start_page | 123 |
container_title | Microbial pathogenesis |
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creator | Thoma-Uszynski, Sybille Ladel, Christoph H. Kaufmann, Stefan H.E. |
description | Although mutant mice lacking
γδT cells resolve
Listeria monocytogenesinfection, extensive abscesses are formed. Manifestation of these inflammatory lesions is prevented by
in vivodepletion with monoclonal antibodies of CD4, CD8 or both T cell subsets. We conclude that these inflammatory tissue reactions develop when αβ T cells of either CD4 or CD8 phenotype are released from control by
γδT cells. |
doi_str_mv | 10.1006/mpat.1996.0095 |
format | Article |
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Listeria monocytogenesinfection, extensive abscesses are formed. Manifestation of these inflammatory lesions is prevented by
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γδT cells resolve
Listeria monocytogenesinfection, extensive abscesses are formed. Manifestation of these inflammatory lesions is prevented by
in vivodepletion with monoclonal antibodies of CD4, CD8 or both T cell subsets. We conclude that these inflammatory tissue reactions develop when αβ T cells of either CD4 or CD8 phenotype are released from control by
γδT cells.</description><subject>abscess formation</subject><subject>Bacterial diseases</subject><subject>Bacteriology</subject><subject>Biological and medical sciences</subject><subject>Experimental bacterial diseases and models</subject><subject>Fundamental and applied biological sciences. Psychology</subject><subject>Infectious diseases</subject><subject>listeriosis</subject><subject>Medical sciences</subject><subject>Microbiology</subject><subject>Pathogenicity, virulence, toxins, bacteriocins, pyrogens, host-bacteria relations, miscellaneous strains</subject><subject>αβ T cells</subject><subject>γδT cells</subject><issn>0882-4010</issn><issn>1096-1208</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>1997</creationdate><recordtype>article</recordtype><recordid>eNotkLtqwzAYhUVpoWnatbOGrk5_WbYuYwi9QaBLOgtF-l1UbDlYSqCP1ctz5Jlqk05n-Tic8xFyy2DBAMR9t7N5wbQWCwBdn5EZAy0KVoI6JzNQqiwqYHBJrlL6gBGpuJ6RdrlNDlOiTT90Noc-0hDpOqSMQ7C062PvPnP_jhFTEWKDLqOnx5_j74Y6bFvqsQkuYMwju09Iu322Maex5dC3B0z0-HX8PrHpmlw0tk14859z8vb4sFk9F-vXp5fVcl0gq0QuPC_RynEfgoJtDdYJByU6JjX3DrFSHpnnoGTpt7XSyjleaclQSC4bAXxO7k69O5ucbZvBRheS2Q2hs8OnKWvBpZIjpk4YjlsOAQeTpicOfRjGn8b3wTAwk1wzyTWTXDPJ5X9PhnM0</recordid><startdate>1997</startdate><enddate>1997</enddate><creator>Thoma-Uszynski, Sybille</creator><creator>Ladel, Christoph H.</creator><creator>Kaufmann, Stefan H.E.</creator><general>Elsevier India Pvt Ltd</general><general>Elsevier</general><scope>IQODW</scope></search><sort><creationdate>1997</creationdate><title>Abscess formation in Listeria monocytogenes-infected γδT cell deficient mouse mutants involves αβT cells</title><author>Thoma-Uszynski, Sybille ; Ladel, Christoph H. ; Kaufmann, Stefan H.E.</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-e146t-d32ea7943e080b50ac6c02ec1793dcee48de1d30872db5898cc34971e6737f603</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>1997</creationdate><topic>abscess formation</topic><topic>Bacterial diseases</topic><topic>Bacteriology</topic><topic>Biological and medical sciences</topic><topic>Experimental bacterial diseases and models</topic><topic>Fundamental and applied biological sciences. Psychology</topic><topic>Infectious diseases</topic><topic>listeriosis</topic><topic>Medical sciences</topic><topic>Microbiology</topic><topic>Pathogenicity, virulence, toxins, bacteriocins, pyrogens, host-bacteria relations, miscellaneous strains</topic><topic>αβ T cells</topic><topic>γδT cells</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Thoma-Uszynski, Sybille</creatorcontrib><creatorcontrib>Ladel, Christoph H.</creatorcontrib><creatorcontrib>Kaufmann, Stefan H.E.</creatorcontrib><collection>Pascal-Francis</collection><jtitle>Microbial pathogenesis</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Thoma-Uszynski, Sybille</au><au>Ladel, Christoph H.</au><au>Kaufmann, Stefan H.E.</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Abscess formation in Listeria monocytogenes-infected γδT cell deficient mouse mutants involves αβT cells</atitle><jtitle>Microbial pathogenesis</jtitle><date>1997</date><risdate>1997</risdate><volume>22</volume><issue>2</issue><spage>123</spage><epage>128</epage><pages>123-128</pages><issn>0882-4010</issn><eissn>1096-1208</eissn><coden>MIPAEV</coden><abstract>Although mutant mice lacking
γδT cells resolve
Listeria monocytogenesinfection, extensive abscesses are formed. Manifestation of these inflammatory lesions is prevented by
in vivodepletion with monoclonal antibodies of CD4, CD8 or both T cell subsets. We conclude that these inflammatory tissue reactions develop when αβ T cells of either CD4 or CD8 phenotype are released from control by
γδT cells.</abstract><cop>Oxford</cop><pub>Elsevier India Pvt Ltd</pub><doi>10.1006/mpat.1996.0095</doi><tpages>6</tpages></addata></record> |
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ispartof | Microbial pathogenesis, 1997, Vol.22 (2), p.123-128 |
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source | Elsevier ScienceDirect Journals Complete |
subjects | abscess formation Bacterial diseases Bacteriology Biological and medical sciences Experimental bacterial diseases and models Fundamental and applied biological sciences. Psychology Infectious diseases listeriosis Medical sciences Microbiology Pathogenicity, virulence, toxins, bacteriocins, pyrogens, host-bacteria relations, miscellaneous strains αβ T cells γδT cells |
title | Abscess formation in Listeria monocytogenes-infected γδT cell deficient mouse mutants involves αβT cells |
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