Emergence of VIM-12 in Enterobacter cloacae

Detection of the blaVIM₋₁₂ gene within the originally described Inh12 integron in a clinical isolate of Enterobacter cloacae is reported for the first time worldwide. Integron Inh12 was carried on a conjugative plasmid of approximately 85 kb which also conferred resistance to aztreonam, likely due t...

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Veröffentlicht in:	Journal of Clinical Microbiology 2010-09, Vol.48 (9), p.3414-3415
Hauptverfasser:	Panopoulou, Maria, Alepopoulou, Eleonora, Ikonomidis, Alexandros, Grapsa, Anastasia, Paspalidou, Eleni, Kartali-Ktenidou, Sofia
Format:	Artikel
Sprache:	eng
Schlagworte:	Anti-Bacterial Agents - pharmacology Bacteriology beta-Lactam Resistance beta-Lactamases - biosynthesis beta-Lactamases - genetics beta-Lactams - pharmacology Biological and medical sciences Enterobacter cloacae Enterobacter cloacae - drug effects Enterobacter cloacae - enzymology Enterobacter cloacae - genetics Enterobacter cloacae - isolation & purification Enterobacteriaceae Infections - microbiology Fundamental and applied biological sciences. Psychology Humans Integrons Microbial Sensitivity Tests Microbiology Miscellaneous Plasmids - analysis
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Zusammenfassung:	Detection of the blaVIM₋₁₂ gene within the originally described Inh12 integron in a clinical isolate of Enterobacter cloacae is reported for the first time worldwide. Integron Inh12 was carried on a conjugative plasmid of approximately 85 kb which also conferred resistance to aztreonam, likely due to AmpC production.
ISSN:	0095-1137 1098-660X
DOI:	10.1128/JCM.00843-10