The pathway of leucine to mevalonate in halophilic archaea: Efficient incorporation of leucine into isoprenoidal lipid with the involvement of isovaleryl-CoA dehydrogenase in Halobacterium salinarum
The pathway of leucine to mevalonate, which has attracted attention in the study of the biosynthesis of isoprenoid in parasitic protozoa and myxobacterium, was observed in the biosynthesis of the lipid core in halophilic archaea. The involvement of isovaleryl-CoA dehydrogenase was strongly suggested...
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Veröffentlicht in: | Bioscience, biotechnology, and biochemistry biotechnology, and biochemistry, 2010, Vol.74 (2), p.443-446 |
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description | The pathway of leucine to mevalonate, which has attracted attention in the study of the biosynthesis of isoprenoid in parasitic protozoa and myxobacterium, was observed in the biosynthesis of the lipid core in halophilic archaea. The involvement of isovaleryl-CoA dehydrogenase was strongly suggested, with stereospecific conversion of the diastereotopic methyl group of leucine to isoprenoidal lipid. |
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The involvement of isovaleryl-CoA dehydrogenase was strongly suggested, with stereospecific conversion of the diastereotopic methyl group of leucine to isoprenoidal lipid.</description><identifier>ISSN: 0916-8451</identifier><identifier>EISSN: 1347-6947</identifier><identifier>DOI: 10.1271/bbb.90814</identifier><identifier>PMID: 20139592</identifier><language>eng</language><publisher>Tokyo: Japan Society for Bioscience, Biotechnology, and Agrochemistry</publisher><subject>Archaea ; Biochemistry ; Biological and medical sciences ; BIOSINTESIS ; BIOSYNTHESE ; BIOSYNTHESIS ; Biotechnology ; diastereotopic methyl group ; Fundamental and applied biological sciences. 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The involvement of isovaleryl-CoA dehydrogenase was strongly suggested, with stereospecific conversion of the diastereotopic methyl group of leucine to isoprenoidal lipid.</description><subject>Archaea</subject><subject>Biochemistry</subject><subject>Biological and medical sciences</subject><subject>BIOSINTESIS</subject><subject>BIOSYNTHESE</subject><subject>BIOSYNTHESIS</subject><subject>Biotechnology</subject><subject>diastereotopic methyl group</subject><subject>Fundamental and applied biological sciences. Psychology</subject><subject>Halobacteriales - genetics</subject><subject>Halobacteriales - metabolism</subject><subject>Halobacterium salinarum</subject><subject>Halobacterium salinarum - genetics</subject><subject>Halobacterium salinarum - metabolism</subject><subject>halophilic archaea</subject><subject>http://www.fao.org/aos/agrovoc#c_36399</subject><subject>http://www.fao.org/aos/agrovoc#c_4292</subject><subject>http://www.fao.org/aos/agrovoc#c_4807</subject><subject>http://www.fao.org/aos/agrovoc#c_928</subject><subject>ISOPRENOIDE</subject><subject>ISOPRENOIDES</subject><subject>ISOPRENOIDS</subject><subject>isovaleryl-CoA dehydrogenase</subject><subject>Isovaleryl-CoA Dehydrogenase - genetics</subject><subject>Isovaleryl-CoA Dehydrogenase - metabolism</subject><subject>LEUCINA</subject><subject>LEUCINE</subject><subject>Leucine - genetics</subject><subject>Leucine - metabolism</subject><subject>Lipids</subject><subject>Lipids - genetics</subject><subject>mevalonate pathway</subject><subject>Mevalonic Acid - metabolism</subject><subject>MICRO-ORGANISME</subject><subject>MICROORGANISMOS</subject><subject>MICROORGANISMS</subject><subject>Pathways</subject><subject>Protozoa</subject><issn>0916-8451</issn><issn>1347-6947</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2010</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><recordid>eNqFkstu1DAUhiMEokNhwQOAvOG2SPEtN3bVqFBQJViUdXTi2I2RY6e2M6N5wT5Xnc4UWKCysmV95__POf6z7CXBJ4RW5GPXdScNrgl_lK0I41VeNrx6nK1wQ8q85gU5yp6F8Avj9FCQp9kRxYQ1RUNX2c3lINEEcdjCDjmFjJyFthJFh0a5AeMsRIm0RUO6T4M2WiDwYgAJn9CZUlpoaWMChPOT8xC1s3_raJuUdHCTl9bpHgwyetI92uo4oDgswMaZjRwXlVSX0OQq_c7ka3eKejnseu-upIVw18Z5aqMDEaXX84gCGG3Bz-Pz7IkCE-SLw3mc_fx8drk-zy--f_m6Pr3IBa-qmEtBe0FxVRRdJTrR8K5kVQOUl5UiiinMe1l3tFdNUReNoKSBvsOKUyiJooSy4-zdXnfy7nqWIbajDkIaA1a6ObQVZwVJOy7_TzJWpJ8pWCLfPkgm37qq-QK-fxAkJacpDhgvfX7Yo8K7ELxU7eT1CH7XEtwumWlTZtq7zCT29UF27kbZ_ybvQ5KANwcAggCjPFihwx-O1jTNsozM95y2yvkRts6bvo2wM87fF7F_-b_alylwLVz5RH37kcxTXCnBjN0CF8noNg</recordid><startdate>2010</startdate><enddate>2010</enddate><creator>Yamauchi, N., Kyushu Univ., Fukuoka (Japan)</creator><general>Japan Society for Bioscience, Biotechnology, and Agrochemistry</general><general>Japan Society for Bioscience Biotechnology and Agrochemistry</general><scope>FBQ</scope><scope>IQODW</scope><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>7TB</scope><scope>7U5</scope><scope>8FD</scope><scope>FR3</scope><scope>L7M</scope><scope>7QO</scope><scope>F1W</scope><scope>H95</scope><scope>L.G</scope><scope>M7N</scope><scope>P64</scope><scope>7X8</scope></search><sort><creationdate>2010</creationdate><title>The pathway of leucine to mevalonate in halophilic archaea: Efficient incorporation of leucine into isoprenoidal lipid with the involvement of isovaleryl-CoA dehydrogenase in Halobacterium salinarum</title><author>Yamauchi, N., Kyushu Univ., Fukuoka (Japan)</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c477t-ec2dc20755b7cbc94b6379a2467f1f3f04de8b2df95859c219adb0f42a61f2123</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2010</creationdate><topic>Archaea</topic><topic>Biochemistry</topic><topic>Biological and medical sciences</topic><topic>BIOSINTESIS</topic><topic>BIOSYNTHESE</topic><topic>BIOSYNTHESIS</topic><topic>Biotechnology</topic><topic>diastereotopic methyl group</topic><topic>Fundamental and applied biological sciences. Psychology</topic><topic>Halobacteriales - genetics</topic><topic>Halobacteriales - metabolism</topic><topic>Halobacterium salinarum</topic><topic>Halobacterium salinarum - genetics</topic><topic>Halobacterium salinarum - metabolism</topic><topic>halophilic archaea</topic><topic>http://www.fao.org/aos/agrovoc#c_36399</topic><topic>http://www.fao.org/aos/agrovoc#c_4292</topic><topic>http://www.fao.org/aos/agrovoc#c_4807</topic><topic>http://www.fao.org/aos/agrovoc#c_928</topic><topic>ISOPRENOIDE</topic><topic>ISOPRENOIDES</topic><topic>ISOPRENOIDS</topic><topic>isovaleryl-CoA dehydrogenase</topic><topic>Isovaleryl-CoA Dehydrogenase - genetics</topic><topic>Isovaleryl-CoA Dehydrogenase - metabolism</topic><topic>LEUCINA</topic><topic>LEUCINE</topic><topic>Leucine - genetics</topic><topic>Leucine - metabolism</topic><topic>Lipids</topic><topic>Lipids - genetics</topic><topic>mevalonate pathway</topic><topic>Mevalonic Acid - metabolism</topic><topic>MICRO-ORGANISME</topic><topic>MICROORGANISMOS</topic><topic>MICROORGANISMS</topic><topic>Pathways</topic><topic>Protozoa</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Yamauchi, N., Kyushu Univ., Fukuoka (Japan)</creatorcontrib><collection>AGRIS</collection><collection>Pascal-Francis</collection><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>Mechanical & Transportation Engineering Abstracts</collection><collection>Solid State and Superconductivity Abstracts</collection><collection>Technology Research Database</collection><collection>Engineering Research Database</collection><collection>Advanced Technologies Database with Aerospace</collection><collection>Biotechnology Research Abstracts</collection><collection>ASFA: Aquatic Sciences and Fisheries Abstracts</collection><collection>Aquatic Science & Fisheries Abstracts (ASFA) 1: Biological Sciences & Living Resources</collection><collection>Aquatic Science & Fisheries Abstracts (ASFA) Professional</collection><collection>Algology Mycology and Protozoology Abstracts (Microbiology C)</collection><collection>Biotechnology and BioEngineering Abstracts</collection><collection>MEDLINE - Academic</collection><jtitle>Bioscience, biotechnology, and biochemistry</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Yamauchi, N., Kyushu Univ., Fukuoka (Japan)</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>The pathway of leucine to mevalonate in halophilic archaea: Efficient incorporation of leucine into isoprenoidal lipid with the involvement of isovaleryl-CoA dehydrogenase in Halobacterium salinarum</atitle><jtitle>Bioscience, biotechnology, and biochemistry</jtitle><addtitle>Biosci Biotechnol Biochem</addtitle><date>2010</date><risdate>2010</risdate><volume>74</volume><issue>2</issue><spage>443</spage><epage>446</epage><pages>443-446</pages><issn>0916-8451</issn><eissn>1347-6947</eissn><abstract>The pathway of leucine to mevalonate, which has attracted attention in the study of the biosynthesis of isoprenoid in parasitic protozoa and myxobacterium, was observed in the biosynthesis of the lipid core in halophilic archaea. 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source | MEDLINE; Elektronische Zeitschriftenbibliothek - Frei zugängliche E-Journals; Oxford University Press Journals All Titles (1996-Current); J-STAGE (Japan Science & Technology Information Aggregator, Electronic) Freely Available Titles - Japanese; Open Access Titles of Japan; Free Full-Text Journals in Chemistry |
subjects | Archaea Biochemistry Biological and medical sciences BIOSINTESIS BIOSYNTHESE BIOSYNTHESIS Biotechnology diastereotopic methyl group Fundamental and applied biological sciences. Psychology Halobacteriales - genetics Halobacteriales - metabolism Halobacterium salinarum Halobacterium salinarum - genetics Halobacterium salinarum - metabolism halophilic archaea http://www.fao.org/aos/agrovoc#c_36399 http://www.fao.org/aos/agrovoc#c_4292 http://www.fao.org/aos/agrovoc#c_4807 http://www.fao.org/aos/agrovoc#c_928 ISOPRENOIDE ISOPRENOIDES ISOPRENOIDS isovaleryl-CoA dehydrogenase Isovaleryl-CoA Dehydrogenase - genetics Isovaleryl-CoA Dehydrogenase - metabolism LEUCINA LEUCINE Leucine - genetics Leucine - metabolism Lipids Lipids - genetics mevalonate pathway Mevalonic Acid - metabolism MICRO-ORGANISME MICROORGANISMOS MICROORGANISMS Pathways Protozoa |
title | The pathway of leucine to mevalonate in halophilic archaea: Efficient incorporation of leucine into isoprenoidal lipid with the involvement of isovaleryl-CoA dehydrogenase in Halobacterium salinarum |
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