Solubility of Flurbiprofen in CO2 and CO2 + Methanol
The solubility of (R,S)-2-(2-fluorobiphenyl-4-yl)propanoic acid (flurbiprofen) in supercritical carbon dioxide and in a mixed solvent consisting of carbon dioxide and methanol at (303.15 and 313.15) K between the pressures of (10.0 and 20.0) MPa is reported. The solubilities were measured using a di...
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| Veröffentlicht in: | Journal of chemical and engineering data 2010-04, Vol.55 (4), p.1542-1546 |
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| container_end_page | 1546 |
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| container_issue | 4 |
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| container_title | Journal of chemical and engineering data |
| container_volume | 55 |
| creator | Chin, Gui Jin Chee, Zi Hui Chen, Wenda Rajendran, Arvind |
| description | The solubility of (R,S)-2-(2-fluorobiphenyl-4-yl)propanoic acid (flurbiprofen) in supercritical carbon dioxide and in a mixed solvent consisting of carbon dioxide and methanol at (303.15 and 313.15) K between the pressures of (10.0 and 20.0) MPa is reported. The solubilities were measured using a direct visualization technique. The experimental data is described using the Peng−Robinson equation of state (PR EoS) together with a one-parameter van der Waals mixing rule. |
| doi_str_mv | 10.1021/je900674t |
| format | Article |
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Chem. Eng. Data</addtitle><description>The solubility of (R,S)-2-(2-fluorobiphenyl-4-yl)propanoic acid (flurbiprofen) in supercritical carbon dioxide and in a mixed solvent consisting of carbon dioxide and methanol at (303.15 and 313.15) K between the pressures of (10.0 and 20.0) MPa is reported. The solubilities were measured using a direct visualization technique. The experimental data is described using the Peng−Robinson equation of state (PR EoS) together with a one-parameter van der Waals mixing rule.</description><subject>Biological and medical sciences</subject><subject>Bones, joints and connective tissue. Antiinflammatory agents</subject><subject>General pharmacology</subject><subject>Medical sciences</subject><subject>Pharmacology. Drug treatments</subject><subject>Physicochemical properties. 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Antiinflammatory agents</topic><topic>General pharmacology</topic><topic>Medical sciences</topic><topic>Pharmacology. Drug treatments</topic><topic>Physicochemical properties. Structure-activity relationships</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Chin, Gui Jin</creatorcontrib><creatorcontrib>Chee, Zi Hui</creatorcontrib><creatorcontrib>Chen, Wenda</creatorcontrib><creatorcontrib>Rajendran, Arvind</creatorcontrib><collection>Pascal-Francis</collection><jtitle>Journal of chemical and engineering data</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Chin, Gui Jin</au><au>Chee, Zi Hui</au><au>Chen, Wenda</au><au>Rajendran, Arvind</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Solubility of Flurbiprofen in CO2 and CO2 + Methanol</atitle><jtitle>Journal of chemical and engineering data</jtitle><addtitle>J. Chem. Eng. Data</addtitle><date>2010-04-08</date><risdate>2010</risdate><volume>55</volume><issue>4</issue><spage>1542</spage><epage>1546</epage><pages>1542-1546</pages><issn>0021-9568</issn><eissn>1520-5134</eissn><coden>JCEAAX</coden><abstract>The solubility of (R,S)-2-(2-fluorobiphenyl-4-yl)propanoic acid (flurbiprofen) in supercritical carbon dioxide and in a mixed solvent consisting of carbon dioxide and methanol at (303.15 and 313.15) K between the pressures of (10.0 and 20.0) MPa is reported. The solubilities were measured using a direct visualization technique. The experimental data is described using the Peng−Robinson equation of state (PR EoS) together with a one-parameter van der Waals mixing rule.</abstract><cop>Washington, DC</cop><pub>American Chemical Society</pub><doi>10.1021/je900674t</doi><tpages>5</tpages></addata></record> |
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| ispartof | Journal of chemical and engineering data, 2010-04, Vol.55 (4), p.1542-1546 |
| issn | 0021-9568 1520-5134 |
| language | eng |
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| source | American Chemical Society Journals |
| subjects | Biological and medical sciences Bones, joints and connective tissue. Antiinflammatory agents General pharmacology Medical sciences Pharmacology. Drug treatments Physicochemical properties. Structure-activity relationships |
| title | Solubility of Flurbiprofen in CO2 and CO2 + Methanol |
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