Comparison of the Xpert Methicillin-Resistant Staphylococcus aureus (MRSA) Assay, BD GeneOhm MRSA Assay, and Culture for Detection of Nasal and Cutaneous Groin Colonization by MRSA

Detection of methicillin (meticillin)-resistant Staphylococcus aureus colonization was assessed using combined nose and groin swabs in two commercial PCR assays (the Xpert MRSA assay and the BD GeneOhm MRSA assay). Compared to routine culture, both had similar sensitivities (87.0% versus 84.8%, resp...

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Veröffentlicht in:	Journal of Clinical Microbiology 2009-11, Vol.47 (11), p.3769-3772
Hauptverfasser:	Kelley, P.G, Grabsch, E.A, Howden, B.P, Gao, W, Grayson, M.L
Format:	Artikel
Sprache:	eng
Schlagworte:	Adolescent Adult Aged Aged, 80 and over Bacteriological Techniques - economics Bacteriological Techniques - methods Bacteriology Biological and medical sciences Carrier State - microbiology Female Fundamental and applied biological sciences. Psychology Groin - microbiology Humans Male Methicillin-Resistant Staphylococcus aureus - genetics Methicillin-Resistant Staphylococcus aureus - growth & development Methicillin-Resistant Staphylococcus aureus - isolation & purification Microbiology Middle Aged Miscellaneous Nasal Cavity - microbiology Polymerase Chain Reaction - economics Polymerase Chain Reaction - methods Sensitivity and Specificity Staphylococcal Infections - microbiology Staphylococcus aureus Time Factors Young Adult
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Zusammenfassung:	Detection of methicillin (meticillin)-resistant Staphylococcus aureus colonization was assessed using combined nose and groin swabs in two commercial PCR assays (the Xpert MRSA assay and the BD GeneOhm MRSA assay). Compared to routine culture, both had similar sensitivities (87.0% versus 84.8%, respectively) and specificities (93.8% versus 92.7%, respectively). Combined PCR assays provide a rapid and more-complete assessment of colonization at a cost similar to that of single-site analysis.
ISSN:	0095-1137 1098-660X
DOI:	10.1128/JCM.00303-09