The discovery and unique pharmacological profile of RO4938581 and R04882224 as potent and selective GABAA α5 inverse agonists for the treatment of cognitive dysfunction

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Veröffentlicht in:	Bioorganic & medicinal chemistry letters 2009, Vol.19 (20), p.5940-5944
Hauptverfasser:	KNUST, Henner, ACHERMANN, Guido, THOMAS, Andrew W, TRUBE, Gerhard, WALDMEIER, Pius, BALLARD, Theresa, BUETTELMANN, Bernd, GASSER, Rodolfo, FISCHER, Holger, HERNANDEZ, Maria-Clemencia, KNOFLACH, Frédéric, KOBLET, Andreas, STADLER, Heinz
Format:	Artikel
Sprache:	eng
Schlagworte:	Biological and medical sciences Gabaergic and benzodiazepinic system Medical sciences Neuropharmacology Neurotransmitters. Neurotransmission. Receptors Pharmacology. Drug treatments Psychoanaleptics: cns stimulant, antidepressant agent, nootropic agent, mood stabilizer Psychoanaleptics: cns stimulant, antidepressant agent, nootropic agent, mood stabilizer..., (alzheimer disease) Psychology. Psychoanalysis. Psychiatry Psychopharmacology
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