Evaluation of GenoType Mycobacteria Direct Assay in Comparison with Gen-Probe Mycobacterium tuberculosis Amplified Direct Test and GenoType MTBDRplus for Direct Detection of Mycobacterium tuberculosis Complex in Clinical Samples

Three molecular assays were evaluated for the direct detection of Mycobacterium tuberculosis complex bacteria in 125 respiratory and 22 nonrespiratory samples. The overall sensitivities obtained were as follows: GenoType MTBDRplus, 97.9%; GenoType Mycobacteria Direct, 93.7%; Gen-Probe Mycobacterium...

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Veröffentlicht in:	Journal of Clinical Microbiology 2009-08, Vol.47 (8), p.2601-2603
Hauptverfasser:	Neonakis, Ioannis K, Gitti, Zoe, Baritaki, Stavroula, Petinaki, Efi, Baritaki, Maria, Spandidos, Demetrios A
Format:	Artikel
Sprache:	eng
Schlagworte:	Bacteriological Techniques - methods Bacteriology Biological and medical sciences Fundamental and applied biological sciences. Psychology Genotype Humans Microbiology Miscellaneous Molecular Diagnostic Techniques - methods Mycobacteriology and Aerobic Actinomycetes Mycobacterium tuberculosis Mycobacterium tuberculosis - genetics Mycobacterium tuberculosis - isolation & purification Sensitivity and Specificity Sputum - microbiology Tuberculosis - diagnosis Tuberculosis - microbiology
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Zusammenfassung:	Three molecular assays were evaluated for the direct detection of Mycobacterium tuberculosis complex bacteria in 125 respiratory and 22 nonrespiratory samples. The overall sensitivities obtained were as follows: GenoType MTBDRplus, 97.9%; GenoType Mycobacteria Direct, 93.7%; Gen-Probe Mycobacterium tuberculosis Amplified Direct Test, 89.6%. The specificity of the assays used was 100%.
ISSN:	0095-1137 1098-660X
DOI:	10.1128/JCM.02351-08