Regional intramuscular pressure development and fatigue in the canine gastrocnemius muscle in situ

Bill T. Ameredes and Mark A. Provenzano Division of Pulmonary, Allergy, and Critical Care Medicine, University of Pittsburgh, Pittsburgh, Pennsylvania 15261 Received 26 March 1997; accepted in final form 31 July 1997. Ameredes, Bill T., and Mark A. Provenzano. Regional intramuscular pressure development and fatigue in the canine gastrocnemius muscle in situ. J. Appl. Physiol. 83(6): 1867-1876, 1997. Intramuscular pressure (P IM ) was measured simultaneously in zones of the medial head of the gastrocnemius-plantaris muscle group (zone I, popliteal origin; zone II, central; zone III, near calcaneus tendon) to determine regional muscle mechanics during isometric tetanic contractions. Peak P IM averages were 586, 1,676, and 993 mmHg deep in zones I, II, and III and 170, 371, and 351 mmHg superficially in zones I, II, and III, respectively. During fatigue, loss of P IM across zones was greatest in zone III ( 81%) and least in zone I ( 60%) when whole muscle tension loss was 49%. Recovery of P IM was greatest in zone III and least in zone II, achieving 86% and 67% of initial P IM , respectively, when tension recovered to 89%. These data demonstrate that 1 ) regional mechanical performance can be measured as P IM within a whole muscle, 2 ) P IM is nonuniform within the canine gastrocnemius-plantaris muscle, being greatest in the deep central zone, and 3 ) fatigue and recovery of P IM are dissimilar across regions. These differences suggest distinct local effects that integrate to determine whole muscle mechanical capacity during and after intense exercise. active tension; blood flow; muscle length; passive tension; preload 0161-7567/97 $5.00 Copyright © 1997 the American Physiological Society