Evolution of Cognitive Deficits and Conversion to Dementia in Patients with Mild Cognitive Impairment: A Very-Long-Term Follow-Up Study

Ten patients with mild cognitive impairment (MCI) underwent extensive neuropsychological evaluation at 12-monthly intervals for a minimum of 6 years. All 10 patients declined and 5 have now died. The onset of dementia, as defined by a fall in global cognitive function (MMSE

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Veröffentlicht in:	Dementia and geriatric cognitive disorders 2006-01, Vol.21 (5-6), p.380-391
Hauptverfasser:	Hodges, John R., Erzinçlioğlu, Sharon, Patterson, Karalyn
Format:	Artikel
Sprache:	eng
Schlagworte:	Activities of Daily Living Aged Alzheimer Disease - diagnosis Alzheimer Disease - epidemiology Alzheimer Disease - physiopathology Biological and medical sciences Brain - physiopathology Cognition Disorders - diagnosis Cognition Disorders - epidemiology Cognition Disorders - physiopathology Degenerative and inherited degenerative diseases of the nervous system. Leukodystrophies. Prion diseases Dementia Dementia - diagnosis Dementia - epidemiology Dementia - physiopathology Diagnostic and Statistical Manual of Mental Disorders Disease Progression Ear, auditive nerve, cochleovestibular tract, facial nerve: diseases, semeiology Female Follow-Up Studies Humans Male Medical sciences Memory Disorders - diagnosis Memory Disorders - epidemiology Neurology Neuropharmacology Neuropsychological Tests Non tumoral diseases Original Research Article Otorhinolaryngology. Stomatology Pharmacology. Drug treatments Psychoanaleptics: cns stimulant, antidepressant agent, nootropic agent, mood stabilizer..., (alzheimer disease) Psychology. Psychoanalysis. Psychiatry Psychopharmacology Semantics Severity of Illness Index
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Zusammenfassung:	Ten patients with mild cognitive impairment (MCI) underwent extensive neuropsychological evaluation at 12-monthly intervals for a minimum of 6 years. All 10 patients declined and 5 have now died. The onset of dementia, as defined by a fall in global cognitive function (MMSE
ISSN:	1420-8008 1421-9824
DOI:	10.1159/000092534