Effect of Exopolymers from Aureobasidium pullulans on Formalin-Induced Chronic Paw Inflammation in Mice

The effects of the exopolymers of Aureobasidium pullulans SM-2001 containing β-1,3/1,6-glucan on formalin-induced chronic inflammation were observed. Doses of 62.5, 125, and 250 mg/kg of the exopolymers were orally administered once a day for 10 days to formalin-induced chronic inflammatory mice (0....

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Veröffentlicht in:	Journal of microbiology and biotechnology 2006-12, Vol.16 (12), p.1954-1960
Hauptverfasser:	Kim, H.D. (Catholic University of Daegu, Gyungsan, Republic of Korea), Cho, H.R. (Glucan Corp. Research Institute, Marine Biotechnology, Busan, Republic of Korea), Moon, S.B. (Glucan Corp. Research Institute, Marine Biotechnology, Busan, Republic of Korea), Shin, H.D. (Glucan Corp. Research Institute, Marine Biotechnology, Busan, Republic of Korea), Yang, K.J. (Glucan Corp. Research Institute, Marine Biotechnology, Busan, Republic of Korea), Park, B.R. (Glucan Corp. Research Institute, Marine Biotechnology, Busan, Republic of Korea), Jang, H.J. (Glucan Corp. Research Institute, Marine Biotechnology, Busan, Republic of Korea), Kim, L.S. (Glucan Corp. Research Institute, Marine Biotechnology, Busan, Republic of Korea), Lee, H.S. (Daegu Haany University, Gyeongsan, Republic of Korea), Ku, S.K. (Dong Wha Pharmaceutical Industrial Co., Ltd., Anyang, Republic of Korea), E-mail: gucci200@hanmail.net
Format:	Artikel
Sprache:	eng
Schlagworte:	AUREOBASIDIUM PULLULANS beta-Glucan Biological and medical sciences Biotechnology chronic inflammation exopolymers Fundamental and applied biological sciences. Psychology HISTOPATHOLOGIE HISTOPATHOLOGY HISTOPATOLOGIA
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Zusammenfassung:	The effects of the exopolymers of Aureobasidium pullulans SM-2001 containing β-1,3/1,6-glucan on formalin-induced chronic inflammation were observed. Doses of 62.5, 125, and 250 mg/kg of the exopolymers were orally administered once a day for 10 days to formalin-induced chronic inflammatory mice (0.02 ml of 3.75% formalin was subaponeurotically injected into the left hind paw), and then the bilateral hind-paw thickness and volume were measured daily, while the paw wet-weight, histological profiles, and histomorphometrical analyses were conducted at termination.
ISSN:	1017-7825