Lactobacillus rhamnosus Strain GG Modulates Intestinal Absorption, Fecal Excretion, and Toxicity of Aflatoxin B₁ in Rats

In this study, the modulation of aflatoxin B₁ (AFB₁) uptake in rats by administration of the probiotic Lactobacillus rhamnosus GG was demonstrated. Fecal AFB₁ excretion in GG-treated rats was increased via bacterial AFB₁ binding. Furthermore, AFB₁-associated growth faltering and liver injury were al...

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Veröffentlicht in:Applied and Environmental Microbiology 2006-11, Vol.72 (11), p.7398-7400
Hauptverfasser: Gratz, S, Täubel, M, Juvonen, R.O, Viluksela, M, Turner, P.C, Mykkänen, H, El-Nezami, H
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container_issue 11
container_start_page 7398
container_title Applied and Environmental Microbiology
container_volume 72
creator Gratz, S
Täubel, M
Juvonen, R.O
Viluksela, M
Turner, P.C
Mykkänen, H
El-Nezami, H
description In this study, the modulation of aflatoxin B₁ (AFB₁) uptake in rats by administration of the probiotic Lactobacillus rhamnosus GG was demonstrated. Fecal AFB₁ excretion in GG-treated rats was increased via bacterial AFB₁ binding. Furthermore, AFB₁-associated growth faltering and liver injury were alleviated with GG treatment.
doi_str_mv 10.1128/AEM.01348-06
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source American Society for Microbiology; PubMed Central; Alma/SFX Local Collection
subjects absorption
aflatoxin B1
binding capacity
Biological and medical sciences
excretion
feces
Food Microbiology
Fundamental and applied biological sciences. Psychology
intestinal absorption
Lactobacillus rhamnosus
Microbiology
probiotics
rats
strains
toxicity
title Lactobacillus rhamnosus Strain GG Modulates Intestinal Absorption, Fecal Excretion, and Toxicity of Aflatoxin B₁ in Rats
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