Lactobacillus rhamnosus Strain GG Modulates Intestinal Absorption, Fecal Excretion, and Toxicity of Aflatoxin B₁ in Rats
In this study, the modulation of aflatoxin B₁ (AFB₁) uptake in rats by administration of the probiotic Lactobacillus rhamnosus GG was demonstrated. Fecal AFB₁ excretion in GG-treated rats was increased via bacterial AFB₁ binding. Furthermore, AFB₁-associated growth faltering and liver injury were al...
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Veröffentlicht in: | Applied and Environmental Microbiology 2006-11, Vol.72 (11), p.7398-7400 |
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container_title | Applied and Environmental Microbiology |
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creator | Gratz, S Täubel, M Juvonen, R.O Viluksela, M Turner, P.C Mykkänen, H El-Nezami, H |
description | In this study, the modulation of aflatoxin B₁ (AFB₁) uptake in rats by administration of the probiotic Lactobacillus rhamnosus GG was demonstrated. Fecal AFB₁ excretion in GG-treated rats was increased via bacterial AFB₁ binding. Furthermore, AFB₁-associated growth faltering and liver injury were alleviated with GG treatment. |
doi_str_mv | 10.1128/AEM.01348-06 |
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Fecal AFB₁ excretion in GG-treated rats was increased via bacterial AFB₁ binding. Furthermore, AFB₁-associated growth faltering and liver injury were alleviated with GG treatment.</description><identifier>ISSN: 0099-2240</identifier><identifier>EISSN: 1098-5336</identifier><identifier>DOI: 10.1128/AEM.01348-06</identifier><identifier>PMID: 16980432</identifier><identifier>CODEN: AEMIDF</identifier><language>eng</language><publisher>Washington, DC: American Society for Microbiology</publisher><subject>absorption ; aflatoxin B1 ; binding capacity ; Biological and medical sciences ; excretion ; feces ; Food Microbiology ; Fundamental and applied biological sciences. 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Fecal AFB₁ excretion in GG-treated rats was increased via bacterial AFB₁ binding. Furthermore, AFB₁-associated growth faltering and liver injury were alleviated with GG treatment.</description><subject>absorption</subject><subject>aflatoxin B1</subject><subject>binding capacity</subject><subject>Biological and medical sciences</subject><subject>excretion</subject><subject>feces</subject><subject>Food Microbiology</subject><subject>Fundamental and applied biological sciences. Psychology</subject><subject>intestinal absorption</subject><subject>Lactobacillus rhamnosus</subject><subject>Microbiology</subject><subject>probiotics</subject><subject>rats</subject><subject>strains</subject><subject>toxicity</subject><issn>0099-2240</issn><issn>1098-5336</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2006</creationdate><recordtype>article</recordtype><recordid>eNpVkcFqGzEQhkVJady0t94rAr11U40ka7WXghscN-BQaJKzmJW0tsquZFbr1umtedQ8SQUOhV5m5p_554NhCHkH7AKA60-L5c0FAyF1xdQLMgPW6GouhDohM8aapuJcslPyOucfjDHJlH5FTkE1mknBZ-T3Gu2UWrSh7_eZjlscYsqlup1GDJGuVvQmuX2Pk8_0OpY4hYg9XbQ5jbsppPiRXnlbOsuDHf2xgdHRu3QINkwPNHV00ZX9oiP98vT4h5b8Haf8hrzssM_-7XM-I_dXy7vLr9X62-r6crGuOhBKVQ40MmTScl0kOCZlXYu6lnNXCy-0aJtWCc2E5BY7BbqZO2511znGHa-9OCOfj9zdvh28sz6W03qzG8OA44NJGMz_kxi2ZpN-GlBCQaMK4MMzAHO5tBsx2pD_AUDzuZa1LL7zo28bNttfYfQG82DQD6bmBsDUotHF9P5o6jAZ3IwFdH_LywMZAEgBWvwF2PKNIQ</recordid><startdate>20061101</startdate><enddate>20061101</enddate><creator>Gratz, S</creator><creator>Täubel, M</creator><creator>Juvonen, R.O</creator><creator>Viluksela, M</creator><creator>Turner, P.C</creator><creator>Mykkänen, H</creator><creator>El-Nezami, H</creator><general>American Society for Microbiology</general><scope>FBQ</scope><scope>IQODW</scope><scope>5PM</scope></search><sort><creationdate>20061101</creationdate><title>Lactobacillus rhamnosus Strain GG Modulates Intestinal Absorption, Fecal Excretion, and Toxicity of Aflatoxin B₁ in Rats</title><author>Gratz, S ; Täubel, M ; Juvonen, R.O ; Viluksela, M ; Turner, P.C ; Mykkänen, H ; El-Nezami, H</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-f1366-d18a0a04c283661d0447737745d73e383b9b6380342caf61895d2c8ffd02d27e3</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2006</creationdate><topic>absorption</topic><topic>aflatoxin B1</topic><topic>binding capacity</topic><topic>Biological and medical sciences</topic><topic>excretion</topic><topic>feces</topic><topic>Food Microbiology</topic><topic>Fundamental and applied biological sciences. Psychology</topic><topic>intestinal absorption</topic><topic>Lactobacillus rhamnosus</topic><topic>Microbiology</topic><topic>probiotics</topic><topic>rats</topic><topic>strains</topic><topic>toxicity</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Gratz, S</creatorcontrib><creatorcontrib>Täubel, M</creatorcontrib><creatorcontrib>Juvonen, R.O</creatorcontrib><creatorcontrib>Viluksela, M</creatorcontrib><creatorcontrib>Turner, P.C</creatorcontrib><creatorcontrib>Mykkänen, H</creatorcontrib><creatorcontrib>El-Nezami, H</creatorcontrib><collection>AGRIS</collection><collection>Pascal-Francis</collection><collection>PubMed Central (Full Participant titles)</collection><jtitle>Applied and Environmental Microbiology</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Gratz, S</au><au>Täubel, M</au><au>Juvonen, R.O</au><au>Viluksela, M</au><au>Turner, P.C</au><au>Mykkänen, H</au><au>El-Nezami, H</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Lactobacillus rhamnosus Strain GG Modulates Intestinal Absorption, Fecal Excretion, and Toxicity of Aflatoxin B₁ in Rats</atitle><jtitle>Applied and Environmental Microbiology</jtitle><date>2006-11-01</date><risdate>2006</risdate><volume>72</volume><issue>11</issue><spage>7398</spage><epage>7400</epage><pages>7398-7400</pages><issn>0099-2240</issn><eissn>1098-5336</eissn><coden>AEMIDF</coden><abstract>In this study, the modulation of aflatoxin B₁ (AFB₁) uptake in rats by administration of the probiotic Lactobacillus rhamnosus GG was demonstrated. Fecal AFB₁ excretion in GG-treated rats was increased via bacterial AFB₁ binding. Furthermore, AFB₁-associated growth faltering and liver injury were alleviated with GG treatment.</abstract><cop>Washington, DC</cop><pub>American Society for Microbiology</pub><pmid>16980432</pmid><doi>10.1128/AEM.01348-06</doi><tpages>3</tpages></addata></record> |
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subjects | absorption aflatoxin B1 binding capacity Biological and medical sciences excretion feces Food Microbiology Fundamental and applied biological sciences. Psychology intestinal absorption Lactobacillus rhamnosus Microbiology probiotics rats strains toxicity |
title | Lactobacillus rhamnosus Strain GG Modulates Intestinal Absorption, Fecal Excretion, and Toxicity of Aflatoxin B₁ in Rats |
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