Lactobacillus rhamnosus Strain GG Modulates Intestinal Absorption, Fecal Excretion, and Toxicity of Aflatoxin B₁ in Rats

Lactobacillus rhamnosus Strain GG Modulates Intestinal Absorption, Fecal Excretion, and Toxicity of Aflatoxin B₁ in Rats

In this study, the modulation of aflatoxin B₁ (AFB₁) uptake in rats by administration of the probiotic Lactobacillus rhamnosus GG was demonstrated. Fecal AFB₁ excretion in GG-treated rats was increased via bacterial AFB₁ binding. Furthermore, AFB₁-associated growth faltering and liver injury were al...

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Veröffentlicht in:Applied and Environmental Microbiology 2006-11, Vol.72 (11), p.7398-7400
Hauptverfasser: Gratz, S, Täubel, M, Juvonen, R.O, Viluksela, M, Turner, P.C, Mykkänen, H, El-Nezami, H
Format: Artikel
Sprache:eng
Schlagworte:
absorption
aflatoxin B1
binding capacity
Biological and medical sciences
excretion
feces
Food Microbiology
Fundamental and applied biological sciences. Psychology
intestinal absorption
Lactobacillus rhamnosus
Microbiology
probiotics
rats
strains
toxicity
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Beschreibung
Zusammenfassung:In this study, the modulation of aflatoxin B₁ (AFB₁) uptake in rats by administration of the probiotic Lactobacillus rhamnosus GG was demonstrated. Fecal AFB₁ excretion in GG-treated rats was increased via bacterial AFB₁ binding. Furthermore, AFB₁-associated growth faltering and liver injury were alleviated with GG treatment.
ISSN:0099-2240
1098-5336
DOI:10.1128/AEM.01348-06