Single molecule recognition of SGLT1 in live G6D3 cells using force spectroscopy

SGLT1, a member of the sodium-dependent glucose co-transporter family, plays a crucial role in the re-absorption of filtered D-glucose in the kidney proximal tubule. The present study extends the AFM investigations to a live cell system in order to obtain direct evidence of SGLT1 recognition in inta...

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Hauptverfasser:	Puntheeranurak, T., Michel, K., Scharlau, D., Kinne, R.K.H., Hinterdorfer, P.
Format:	Tagungsbericht
Sprache:	eng
Schlagworte:	Atomic force microscopes Atomic force microscopy Biomembranes Biophysics Brushes Cells (biology) Communication, education, history, and philosophy Exact sciences and technology General equipment and techniques Instruments, apparatus, components and techniques common to several branches of physics and astronomy Kinetic theory Physics Physics literature and publications Physiology Proteins Scanning probe microscopes, components and techniques Sensors (chemical, optical, electrical, movement, gas, etc.) remote sensing Spectroscopy Sugar
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Beschreibung
Zusammenfassung:	SGLT1, a member of the sodium-dependent glucose co-transporter family, plays a crucial role in the re-absorption of filtered D-glucose in the kidney proximal tubule. The present study extends the AFM investigations to a live cell system in order to obtain direct evidence of SGLT1 recognition in intact cell membranes.
DOI:	10.1109/ICSENS.2004.1426404