Second-line treatment of postmenopausal women with advanced breast carcinoma

Breast cancer is the most prevalent cancer in women and, currently, there is no standard of care for the treatment of metastatic disease. Treatment options are based on a number of tumor- and patient-related factors. This review explores some of these options, including the use of hormonal manipulat...

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Veröffentlicht in:	Expert review of anticancer therapy 2006-04, Vol.6 (4), p.613-624
Hauptverfasser:	Board, Ruth E, Dean, Emma J, Mitchell, Claire, Wardley, Andrew M
Format:	Artikel
Sprache:	eng
Schlagworte:	Antineoplastic agents Antineoplastic Agents - administration & dosage Antineoplastic Agents, Hormonal - administration & dosage aromatase inhibitors Biological and medical sciences Breast cancer Breast Neoplasms - drug therapy Breast Neoplasms - metabolism Cancer Care and treatment chemotherapy Drug Delivery Systems - methods Drug Delivery Systems - trends Female Gynecology. Andrology. Obstetrics Humans Mammary gland diseases Medical sciences Pharmacology. Drug treatments postmenopausal Postmenopausal women Postmenopause - drug effects Postmenopause - metabolism tamoxifen trastuzumab treatment Tumors
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Beschreibung
Zusammenfassung:	Breast cancer is the most prevalent cancer in women and, currently, there is no standard of care for the treatment of metastatic disease. Treatment options are based on a number of tumor- and patient-related factors. This review explores some of these options, including the use of hormonal manipulation in the treatment of hormone-positive disease, current chemotherapy options and the use of targeted therapies, such as trastuzumab.
ISSN:	1473-7140 1744-8328
DOI:	10.1586/14737140.6.4.613