Successful treatment of visceral leishmaniasis with fluconazole and allopurinol in a patient with renal failure

Standard treatments for visceral leishmaniasis (antimonials, amphotericin B and pentamidine) pose several problems. Failure of antimonials or severe toxicity is particularly troublesome in patients with renal insufficiency. We report a case of visceral leishmaniaisis and renal insufficiency successf...

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Veröffentlicht in:	Scandinavian journal of infectious diseases 2006, Vol.38 (3), p.208-210
Hauptverfasser:	Colakoglu, Murat, Fidan Yaylali&, Guzin, Yalcin Colakoglu, Nagihan, Yilmaz, Mustafa
Format:	Artikel
Sprache:	eng
Schlagworte:	Allopurinol - therapeutic use Animals Antibiotics. Antiinfectious agents. Antiparasitic agents Antifungal agents Antimetabolites - therapeutic use Antiprotozoal Agents - therapeutic use Biological and medical sciences Diabetic Nephropathies - complications Drug Therapy, Combination Fluconazole - therapeutic use Human protozoal diseases Humans Infectious diseases Leishmaniasis, Visceral - complications Leishmaniasis, Visceral - drug therapy Leshmaniasis Male Medical sciences Middle Aged Nephrology. Urinary tract diseases Nephropathies. Renovascular diseases. Renal failure Parasitic diseases Pharmacology. Drug treatments Protozoal diseases Renal failure Renal Insufficiency - complications Treatment Outcome
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Zusammenfassung:	Standard treatments for visceral leishmaniasis (antimonials, amphotericin B and pentamidine) pose several problems. Failure of antimonials or severe toxicity is particularly troublesome in patients with renal insufficiency. We report a case of visceral leishmaniaisis and renal insufficiency successfully treated with fluconazole and allopurinol for 4 months.
ISSN:	0036-5548 1651-1980
DOI:	10.1080/00365540500321405