Discovery of a substituted 8-arylquinoline series of PED4 inhibitors : Structure-activity relationship, optimization, and identification of a highly potent, well tolerated, PDE4 inhibitor

Bibliographische Detailangaben

Veröffentlicht in:	Bioorganic & medicinal chemistry letters 2005, Vol.15 (23), p.5241-5246
Hauptverfasser:	MACDONALD, Dwight, MASTRACCHIO, Anthony, CHUN LI, TRIMBLE, Laird A, DAY, Stephen, CHAURET, Nathalie, NICOLL-GRIFFITH, Deborah A, SILVA, Jose M, ZHENG HUANG, LALIBERTE, France, LIU, Susana, ETHIER, Diane, PERRIER, Hélène, PON, Doug, MUISE, Eric, BOULET, Louise, CHI CHUNG CHAN, STYHLER, Angela, CHARLESON, Stella, MANCINI, Joseph, MASSON, Paul, CLAVEAU, David, NICHOLSON, Donald, DUBE, Daniel, TURNER, Mervyn, YOUNG, Robert N, GIRARD, Yves, GALLANT, Michel, LACOMBE, Patrick, DESCHENES, Denis, ROY, Bruno, SCHEIGETZ, John, BATEMAN, Kevin
Format:	Artikel
Sprache:	eng
Schlagworte:	Biological and medical sciences Medical sciences Pharmacology. Drug treatments Respiratory system
Online-Zugang:	Volltext
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