Antibodies from Patients with Melioidosis Recognize Burkholderia mallei but Not Burkholderia thailandensis Antigens in the Indirect Hemagglutination Assay

Antibodies from Patients with Melioidosis Recognize Burkholderia mallei but Not Burkholderia thailandensis Antigens in the Indirect Hemagglutination Assay

The indirect hemagglutination assay routinely used to detect antibodies to Burkholderia pseudomallei was modified to detect cross-reactivity of antibodies to B. pseudomallei, B. mallei, and B. thailandensis antigens. We demonstrate a lack of cross-reactivity between B. pseudomallei and B. thailanden...

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Veröffentlicht in:Journal of Clinical Microbiology 2005-09, Vol.43 (9), p.4872-4874
Hauptverfasser: Tiyawisutsri, Rachaneeporn, Peacock, Sharon J, Langa, Sayan, Limmathurotsakul, Direk, Cheng, Allen C, Chierakul, Wirongrong, Chaowagul, Wipada, Day, Nicholas P. J, Wuthiekanun, Vanaporn
Format: Artikel
Sprache:eng
Schlagworte:
Adolescent
Adult
Aged
Aged, 80 and over
Antibodies, Bacterial - blood
Antibodies, Bacterial - immunology
Antigens, Bacterial - immunology
Bacterial diseases
Bacteriology
Biological and medical sciences
Burkholderia - immunology
Burkholderia mallei
Burkholderia mallei - immunology
Burkholderia pseudomallei
Burkholderia thailandensis
Cross Reactions
Female
Fundamental and applied biological sciences. Psychology
Hemagglutination Tests
Human bacterial diseases
Humans
Infectious diseases
Male
Medical sciences
Melioidosis
Melioidosis - immunology
Melioidosis - microbiology
Microbiology
Middle Aged
Miscellaneous
Tropical bacterial diseases
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Beschreibung
Zusammenfassung:The indirect hemagglutination assay routinely used to detect antibodies to Burkholderia pseudomallei was modified to detect cross-reactivity of antibodies to B. pseudomallei, B. mallei, and B. thailandensis antigens. We demonstrate a lack of cross-reactivity between B. pseudomallei and B. thailandensis but marked cross-reactivity between B. pseudomallei and B. mallei.
ISSN:0095-1137
1098-660X
DOI:10.1128/JCM.43.9.4872-4874.2005