Pocket Recognition on a Protein Using Euclidean Voronoi Diagram of Atoms

Proteins consist of atoms. Given a protein, the automatic recognition of depressed regions, called pockets, on the surface of the protein is important for protein-ligand docking and facilitates fast development of new drugs. Recently, computational approaches for the recognition of pockets have emerged. Presented in this paper is a geometric method for the pocket recognition based on Voronoi diagram for atoms in Euclidean distance metric.