Efficacy, Plasma Pharmacokinetics, and Safety of Icofungipen, an Inhibitor of Candida Isoleucyl-tRNA Synthetase, in Treatment of Experimental Disseminated Candidiasis in Persistently Neutropenic Rabbits

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Veröffentlicht in:	Antimicrobial Agents and Chemotherapy 2005-05, Vol.49 (5), p.2084-2092
Hauptverfasser:	PETRAITIENE, Ruta, PETRAITIS, Vidmantas, KELAHER, Amy M, SARAFANDI, Alia A, MICKIENE, Diana, GROLL, Andreas H, SEIN, Tin, BACHER, John, WALSH, Thomas J
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Antibiotics. Antiinfectious agents. Antiparasitic agents Antifungal Agents Antifungal Agents - adverse effects Antifungal Agents - pharmacokinetics Antifungal Agents - pharmacology Biological and medical sciences Candida albicans Candida albicans - drug effects Candida albicans - enzymology Candida albicans - ultrastructure Candidiasis Candidiasis - drug therapy Candidiasis - microbiology Culture Media Cycloleucine Cycloleucine - adverse effects Cycloleucine - analogs & derivatives Cycloleucine - pharmacokinetics Cycloleucine - pharmacology Experimental Therapeutics Female Immunosuppression Isoleucine-tRNA Ligase Isoleucine-tRNA Ligase - antagonists & inhibitors Kidney - microbiology Liver - microbiology Medical sciences Neutropenia Neutropenia - complications Pharmacology. Drug treatments Rabbits Spleen - microbiology
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Zusammenfassung:	Classifications Services AAC Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley Reddit StumbleUpon Twitter current issue AAC About AAC Subscribers Authors Reviewers Advertisers Inquiries from the Press Permissions & Commercial Reprints ASM Journals Public Access Policy AAC RSS Feeds 1752 N Street N.W. • Washington DC 20036 202.737.3600 • 202.942.9355 fax • journals@asmusa.org Print ISSN: 0066-4804 Online ISSN: 1098-6596 Copyright © 2014 by the American Society for Microbiology. For an alternate route to AAC .asm.org, visit: AAC
ISSN:	0066-4804 1098-6596
DOI:	10.1128/AAC.49.5.2084-2092.2005