Effects of morphine and hashish (Cannabis sativa) on activities of human red blood cell carbonic anhydrase isoenzymes

Carbonic anhydrase (CA) exists in all living organisms and converts CO2 (waste product) to H2CO3. Two different forms of CA are present in human erythrocytes. These forms are known as CA-I and CA-II. Whereas CA-I has a low activity, CA-II is highly active. In the current study, CA-I and CA-II were p...

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Veröffentlicht in:	Pharmaceutical biology 2004-01, Vol.42 (6), p.434-439
Hauptverfasser:	Demir, Y, Alayli, A, Demir, N
Format:	Artikel
Sprache:	eng
Schlagworte:	Affinity chromatography Biological and medical sciences carbonic anhydrase General pharmacology hashish (Cannabis sativa) Medical sciences morphine Pharmacognosy. Homeopathy. Health food Pharmacology. Drug treatments
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Zusammenfassung:	Carbonic anhydrase (CA) exists in all living organisms and converts CO2 (waste product) to H2CO3. Two different forms of CA are present in human erythrocytes. These forms are known as CA-I and CA-II. Whereas CA-I has a low activity, CA-II is highly active. In the current study, CA-I and CA-II were purified by affinity chromatography from human blood. Then the effects of hashish (Cannabis sativa L.) and morphine on the CA-I and CA-II activities were measured by following esterase activity, and the results are presented.
ISSN:	1388-0209 1744-5116
DOI:	10.1080/13880200490886094