Antifungal flavonoids from Ballota glandulosissima

Abstract The flavonoids kumatakenin (1), pachypodol (2), 5-hydroxy-7,3′,4′-trimethoxyflavone (3), velutin (4), salvigenin (5), retusin (6) and corymbosin (7) have been isolated from the aerial parts of Ballota glandulosissima Hub.-Mor & Patzak. Among them, 2-4 and 7 have not been reported previo...

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Veröffentlicht in:	Pharmaceutical biology 2003, Vol.41 (7), p.483-486
Hauptverfasser:	Citoglu, G.S, Sever, B, Antus, S, Baitz-Gacs, E, Altanlar, N
Format:	Artikel
Sprache:	eng
Schlagworte:	5-hydroxy-7,3′,4′-trimethoxyflavone aerial parts antibacterial properties Antifungal activity antifungal properties Bacillus subtilis Ballota Ballota glandulosissima Ballota glandulosissima Hub.-Mor & Patzak Biological and medical sciences Candida albicans Candida krusei chemical structure corymbosin flavonoids General pharmacology isolation kumatakenin Lamiaceae Medical sciences medicinal plants pachypodol Pharmacognosy. Homeopathy. Health food Pharmacology. Drug treatments Pseudomonas aeruginosa retusin salvigenin spectral analysis Staphylococcus aureus traditional medicine velutin
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Zusammenfassung:	Abstract The flavonoids kumatakenin (1), pachypodol (2), 5-hydroxy-7,3′,4′-trimethoxyflavone (3), velutin (4), salvigenin (5), retusin (6) and corymbosin (7) have been isolated from the aerial parts of Ballota glandulosissima Hub.-Mor & Patzak. Among them, 2-4 and 7 have not been reported previously in the genus Ballota. The antibacterial and antifungal activities of 1-4 and 6 were tested against Bacillus subtilis, Staphylococcus aureus, Staphylococcus faecalis, Echerichia coli, Pseudomonas aeruginosa, Candida albicans, Candida krusei and Candida galabrata.
ISSN:	1388-0209 1744-5116
DOI:	10.1080/13880200308951339