rdxA Gene is an Unlikely Marker for Metronidazole Resistance in the Asian Helicobacter pylori Isolates

rdxA Gene is an Unlikely Marker for Metronidazole Resistance in the Asian Helicobacter pylori Isolates

Mutations in the rdxA gene had been reported to be associated with metronidazole resistance in Helicobacter pylori. In this study, sensitivity to metronidazole, RAPD profiles, and DNA sequences of the rdxA gene of 32 local H. pylori isolates were analyzed . Of these, 13 were found to be resistant, w...

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Veröffentlicht in:Journal of microbiology and biotechnology 2003-10, Vol.13 (5), p.751-758
Hauptverfasser: Lui, S.Y, Ho, B. (National University of Singapore, Singapore, Republic of Korea), Ling, K.L. (Singapore General Hospital, Singapore, Singapore)
Format: Artikel
Sprache:eng
Schlagworte:
Biological and medical sciences
Biotechnology
Fundamental and applied biological sciences. Psychology
helicobacter pylori
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Zusammenfassung:Mutations in the rdxA gene had been reported to be associated with metronidazole resistance in Helicobacter pylori. In this study, sensitivity to metronidazole, RAPD profiles, and DNA sequences of the rdxA gene of 32 local H. pylori isolates were analyzed . Of these, 13 were found to be resistant, while 19 were sensitive to metonidazole. Among the 32 isolates, 10 were paired isolates from the antrum and body of the stomach of individual patients.
ISSN:1017-7825