Microfracture of a Baclofen Pump Catheter with Intermittent Under- and Overdose
An 8-year-old boy with an implanted intrathecal baclofen pump presented with intermittent signs of baclofen under- and overdose. Pump interrogation, pump volumes, plain X-rays, catheter contrast fluoroscopy and CT of the intrathecal catheter tip were unremarkable. A microfracture of the extradural c...
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| Veröffentlicht in: | Pediatric neurosurgery 2003-09, Vol.39 (3), p.144-148 |
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| creator | Dawes, William J. Drake, James M. Fehlings, Darcy |
| description | An 8-year-old boy with an implanted intrathecal baclofen pump presented with intermittent signs of baclofen under- and overdose. Pump interrogation, pump volumes, plain X-rays, catheter contrast fluoroscopy and CT of the intrathecal catheter tip were unremarkable. A microfracture of the extradural catheter was only seen at a magnification of ×20 and confirmed by scanning electron microscopy. Symptoms resolved following replacement. Microfracture of the intrathecal catheter of baclofen pump systems may present puzzling symptomatology and be difficult to diagnose by conventional means. |
| doi_str_mv | 10.1159/000071652 |
| format | Article |
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Pump interrogation, pump volumes, plain X-rays, catheter contrast fluoroscopy and CT of the intrathecal catheter tip were unremarkable. A microfracture of the extradural catheter was only seen at a magnification of ×20 and confirmed by scanning electron microscopy. Symptoms resolved following replacement. Microfracture of the intrathecal catheter of baclofen pump systems may present puzzling symptomatology and be difficult to diagnose by conventional means.</description><identifier>ISSN: 1016-2291</identifier><identifier>EISSN: 1423-0305</identifier><identifier>DOI: 10.1159/000071652</identifier><identifier>PMID: 12876394</identifier><identifier>CODEN: PDNEEV</identifier><language>eng</language><publisher>Basel, Switzerland: Karger</publisher><subject>Baclofen - administration & dosage ; Biological and medical sciences ; Catheters, Indwelling - adverse effects ; Child ; Dose-Response Relationship, Drug ; Drug Overdose - etiology ; Equipment Failure ; Humans ; Infusion Pumps, Implantable ; Injections, Spinal - adverse effects ; Male ; Medical sciences ; Muscle ; Muscle Relaxants, Central - administration & dosage ; Original Paper ; Pharmacology. Drug treatments</subject><ispartof>Pediatric neurosurgery, 2003-09, Vol.39 (3), p.144-148</ispartof><rights>2003 S. 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Pump interrogation, pump volumes, plain X-rays, catheter contrast fluoroscopy and CT of the intrathecal catheter tip were unremarkable. A microfracture of the extradural catheter was only seen at a magnification of ×20 and confirmed by scanning electron microscopy. Symptoms resolved following replacement. Microfracture of the intrathecal catheter of baclofen pump systems may present puzzling symptomatology and be difficult to diagnose by conventional means.</description><subject>Baclofen - administration & dosage</subject><subject>Biological and medical sciences</subject><subject>Catheters, Indwelling - adverse effects</subject><subject>Child</subject><subject>Dose-Response Relationship, Drug</subject><subject>Drug Overdose - etiology</subject><subject>Equipment Failure</subject><subject>Humans</subject><subject>Infusion Pumps, Implantable</subject><subject>Injections, Spinal - adverse effects</subject><subject>Male</subject><subject>Medical sciences</subject><subject>Muscle</subject><subject>Muscle Relaxants, Central - administration & dosage</subject><subject>Original Paper</subject><subject>Pharmacology. 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Drug treatments</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Dawes, William J.</creatorcontrib><creatorcontrib>Drake, James M.</creatorcontrib><creatorcontrib>Fehlings, Darcy</creatorcontrib><collection>Pascal-Francis</collection><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>ProQuest Central (Corporate)</collection><collection>Neurosciences Abstracts</collection><collection>Health & Medical Collection</collection><collection>ProQuest Central (purchase pre-March 2016)</collection><collection>Medical Database (Alumni Edition)</collection><collection>ProQuest Pharma Collection</collection><collection>Hospital Premium Collection</collection><collection>Hospital Premium Collection (Alumni Edition)</collection><collection>ProQuest Central (Alumni) (purchase pre-March 2016)</collection><collection>Research Library (Alumni Edition)</collection><collection>ProQuest Central (Alumni Edition)</collection><collection>ProQuest Central UK/Ireland</collection><collection>ProQuest Central Essentials</collection><collection>ProQuest Central</collection><collection>ProQuest One Community College</collection><collection>ProQuest Central Korea</collection><collection>Health Research Premium Collection</collection><collection>Health Research Premium Collection (Alumni)</collection><collection>ProQuest Central Student</collection><collection>Research Library Prep</collection><collection>ProQuest Health & Medical Complete (Alumni)</collection><collection>ABI/INFORM Professional Advanced</collection><collection>Health & Medical Collection (Alumni Edition)</collection><collection>Medical Database</collection><collection>Research Library</collection><collection>Research Library (Corporate)</collection><collection>ProQuest One Academic Eastern Edition (DO NOT USE)</collection><collection>ProQuest One Academic</collection><collection>ProQuest One Academic UKI Edition</collection><collection>ProQuest Central China</collection><collection>ProQuest Central Basic</collection><jtitle>Pediatric neurosurgery</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Dawes, William J.</au><au>Drake, James M.</au><au>Fehlings, Darcy</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Microfracture of a Baclofen Pump Catheter with Intermittent Under- and Overdose</atitle><jtitle>Pediatric neurosurgery</jtitle><addtitle>Pediatr Neurosurg</addtitle><date>2003-09-01</date><risdate>2003</risdate><volume>39</volume><issue>3</issue><spage>144</spage><epage>148</epage><pages>144-148</pages><issn>1016-2291</issn><eissn>1423-0305</eissn><coden>PDNEEV</coden><abstract>An 8-year-old boy with an implanted intrathecal baclofen pump presented with intermittent signs of baclofen under- and overdose. Pump interrogation, pump volumes, plain X-rays, catheter contrast fluoroscopy and CT of the intrathecal catheter tip were unremarkable. A microfracture of the extradural catheter was only seen at a magnification of ×20 and confirmed by scanning electron microscopy. Symptoms resolved following replacement. Microfracture of the intrathecal catheter of baclofen pump systems may present puzzling symptomatology and be difficult to diagnose by conventional means.</abstract><cop>Basel, Switzerland</cop><pub>Karger</pub><pmid>12876394</pmid><doi>10.1159/000071652</doi><tpages>5</tpages></addata></record> |
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| ispartof | Pediatric neurosurgery, 2003-09, Vol.39 (3), p.144-148 |
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| source | Karger Journals; MEDLINE |
| subjects | Baclofen - administration & dosage Biological and medical sciences Catheters, Indwelling - adverse effects Child Dose-Response Relationship, Drug Drug Overdose - etiology Equipment Failure Humans Infusion Pumps, Implantable Injections, Spinal - adverse effects Male Medical sciences Muscle Muscle Relaxants, Central - administration & dosage Original Paper Pharmacology. Drug treatments |
| title | Microfracture of a Baclofen Pump Catheter with Intermittent Under- and Overdose |
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