Microfracture of a Baclofen Pump Catheter with Intermittent Under- and Overdose

Microfracture of a Baclofen Pump Catheter with Intermittent Under- and Overdose

An 8-year-old boy with an implanted intrathecal baclofen pump presented with intermittent signs of baclofen under- and overdose. Pump interrogation, pump volumes, plain X-rays, catheter contrast fluoroscopy and CT of the intrathecal catheter tip were unremarkable. A microfracture of the extradural c...

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Veröffentlicht in:Pediatric neurosurgery 2003-09, Vol.39 (3), p.144-148
Hauptverfasser: Dawes, William J., Drake, James M., Fehlings, Darcy
Format: Artikel
Sprache:eng
Schlagworte:
Baclofen - administration & dosage
Biological and medical sciences
Catheters, Indwelling - adverse effects
Child
Dose-Response Relationship, Drug
Drug Overdose - etiology
Equipment Failure
Humans
Infusion Pumps, Implantable
Injections, Spinal - adverse effects
Male
Medical sciences
Muscle
Muscle Relaxants, Central - administration & dosage
Original Paper
Pharmacology. Drug treatments
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Zusammenfassung:An 8-year-old boy with an implanted intrathecal baclofen pump presented with intermittent signs of baclofen under- and overdose. Pump interrogation, pump volumes, plain X-rays, catheter contrast fluoroscopy and CT of the intrathecal catheter tip were unremarkable. A microfracture of the extradural catheter was only seen at a magnification of ×20 and confirmed by scanning electron microscopy. Symptoms resolved following replacement. Microfracture of the intrathecal catheter of baclofen pump systems may present puzzling symptomatology and be difficult to diagnose by conventional means.
ISSN:1016-2291
1423-0305
DOI:10.1159/000071652