Intestinal Candida Phospholipase is not Elevated in Patients with Antibiotic-associated Diarrhea

In order to assess the role of Candida-secreted phospholipase in antibiotic-associated diarrhea (AAD), 43 fecal Candida isolates from patients with AAD and from controls were tested on egg yolk agar for production of phospholipase. Phospholipase zones did not differ between the isolates from patient...

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Veröffentlicht in:	Scandinavian journal of infectious diseases 2002, Vol.34 (11), p.815-816
Hauptverfasser:	Krause, Robert, Haberl, Renate, Strempfl, Christina, Daxböck, Florian, Krejs, Günter J., Reisinger, Emil C., Wenisch, Christoph
Format:	Artikel
Sprache:	eng
Schlagworte:	Anti-Bacterial Agents - adverse effects Antibacterial agents Antibiotics. Antiinfectious agents. Antiparasitic agents Biological and medical sciences Candida - enzymology Candida - pathogenicity Candidiasis - complications Candidiasis - microbiology Diarrhea - chemically induced Diarrhea - complications Diarrhea - microbiology Humans Intestines - microbiology Medical sciences Pharmacology. Drug treatments Phospholipases - analysis Phospholipases - metabolism
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Zusammenfassung:	In order to assess the role of Candida-secreted phospholipase in antibiotic-associated diarrhea (AAD), 43 fecal Candida isolates from patients with AAD and from controls were tested on egg yolk agar for production of phospholipase. Phospholipase zones did not differ between the isolates from patients with AAD and from controls. The data indicate that the fungal virulence factor phospholipase may not be responsible for AAD in adults.
ISSN:	0036-5548 1651-1980
DOI:	10.1080/0036554021000026951