Cytotoxic Effects of Korean Medicinal Herbs determined with Hepatocellular Carcinoma Cell Lines

The cytotoxic potential of 160 crude extracts from 80 kinds of Korean medicinal herbs was evaluated with cultured human hepatocellular carcinoma cells, Hep3B and HepG2. Aqueous extracts of Caesalpinia sappan, Coptis chinenis, and Lepidium apetalum, and methanol extracts of Angelica gigas, Areca cate...

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Veröffentlicht in:	Pharmaceutical biology 2002, Vol.40 (3), p.189-195
Hauptverfasser:	Park, Kap Joo, Yang, Seunghye, Eun, Young Ah, Kim, Soo Young, Lee, Hyung Hoan, Kang, Hyunmin
Format:	Artikel
Sprache:	eng
Schlagworte:	Biological and medical sciences General pharmacology Medical sciences Pharmacognosy. Homeopathy. Health food Pharmacology. Drug treatments
Online-Zugang:	Volltext
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Zusammenfassung:	The cytotoxic potential of 160 crude extracts from 80 kinds of Korean medicinal herbs was evaluated with cultured human hepatocellular carcinoma cells, Hep3B and HepG2. Aqueous extracts of Caesalpinia sappan, Coptis chinenis, and Lepidium apetalum, and methanol extracts of Angelica gigas, Areca catechu, C. sappan, C. chinensis, Ephedra sinica, L. apetalum, Magnolia obovata, Peucedanum praeruptorum, and Rheum palmatum, were active against Hep3B. Aqueous extracts of C. sappan, C. chinensis, L. apetalum, and P. praeruptorum, and methanol extracts of A. catechu, C. sappan, Cinnamomum cassia, C. chinensis, L. apetalum, M. obovata, P. praeruptorum, and U. pumila, exhibited cytotoxic activity against HepG2.
ISSN:	1388-0209 1744-5116
DOI:	10.1076/phbi.40.3.189.5824