Medical Management of Eosinophilic Granuloma of the Cervical Spine

We report a case of eosinophilic granuloma involving the vertebral bodies of the cervical spine in a 33-month-old girl. This lesion was diagnosed by needle biopsy and treated with prednisone and vinblastine therapy along with immobilization in a Minerva brace. The child has done well over a 9-month...

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Veröffentlicht in:	Pediatric neurosurgery 1999-09, Vol.31 (3), p.159-162
Hauptverfasser:	Levy, Elad I., Scarrow, Alan, Hamilton, Ronald C., Wollman, Michael R., Fitz, Charles, Pollack, Ian F.
Format:	Artikel
Sprache:	eng
Schlagworte:	Anti-Inflammatory Agents - administration & dosage Antineoplastic Agents, Phytogenic - administration & dosage Biological and medical sciences Biopsy, Needle Braces Case Report Cervical Vertebrae - pathology Child, Preschool Drug Therapy, Combination Eosinophilic Granuloma - drug therapy Eosinophilic Granuloma - pathology Female Follow-Up Studies Hematologic and hematopoietic diseases Humans Magnetic Resonance Imaging Medical sciences Other diseases. Hematologic involvement in other diseases Prednisone - administration & dosage Spinal Diseases - drug therapy Spinal Diseases - pathology Vinblastine - administration & dosage
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Zusammenfassung:	We report a case of eosinophilic granuloma involving the vertebral bodies of the cervical spine in a 33-month-old girl. This lesion was diagnosed by needle biopsy and treated with prednisone and vinblastine therapy along with immobilization in a Minerva brace. The child has done well over a 9-month follow-up and has shown MRI evidence of resolution of the lesion, reestablishment of structural integrity within the cervical spine and potential reconstitution of the involved vertebral bodies.
ISSN:	1016-2291 1423-0305
DOI:	10.1159/000028853