181A MULTICENTRE EVALUATION OF THE AUTOGRAFT PROCEDURE FOR YOUNG PATIENTS UNDERGOING AORTIC VALVE REPLACEMENT: RESULTS FROM THE GERMAN ROSS REGISTRY

Objectives: Conventional aortic valve replacement (AVR) in the young, active patient represents a suboptimal solution, in terms of long-term survival and quality of life. The aim of the present work is to present our multicentre results with the pulmonary autograft in young patient undergoing aortic valve replacement. Methods: Between 1992 and 2013, 1967 patients (1786 adults; 41.6 ± 15.1 years) underwent AVR with the pulmonary autograft principle in 9 centres. All patients underwent prospective clinical and echocardiographic examinations, annually. Mean follow-up was 7.7 ± 4.8 years (range 0–23) with a total cumulative follow-up of 14,571 years with 635 patients having a follow-up of at least 10 years. Results: In-hospital mortality was 1.37% (n = 26). Late survival of the adult population was comparable to the age- and gender-matched general population (observed deaths: 90, expected deaths: 70; P = 0.439). Freedom from autograft reoperation at 5, 10 and 15 years was 97.8%, 95.9% and 89.6%, respectively, whereas freedom from homograft reoperation was 98.4%, 96.6% and 94.6%, respectively. Overall freedom from reoperation was 96.2%, 92.8% and 86.2%, respectively. Longitudinal modelling of functional valve characteristics revealed a low (