P-183EARLY TERM RESULTS OF A COMPARISON BETWEEN GENERAL ANAESTHESIA AND SEDOANALGESIA IN INTERSTITIAL LUNG DISEASE: A RANDOMIZED PROSPECTIVE STUDY

Objectives: Tissue biopsy in diagnosis of interstitial lung disease (ILD) is generally carried out with general anaesthesia. In the study, we performed wedge biopsy under sedoanalgesia without the need for intubation or muscle relaxant agents via single port. The aim of this report is to compare impact on morbidity of wedge biopsy between patients under sedoanalgesia and video-assisted thoracoscopic surgery. Methods: Between March 2013 and July 2013 wedge resection was performed on both groups with VATS or sedoanalgesia randomly. General anaesthesia patients (n = 5) were named Group 1, while sedoanalgesia patients (n = 5) were Group 2. Midazolam and fentanyl was given to patients in Group 2. The visual analogue scale (VAS) was used to determine pain classification. The groups were compared in terms of age, sex, operation time, complication, mortality and postoperative pain. Results: Mean age was 44.1. In Group 1 average operation time was 50 min, whereas it was 38 min in Group 2. One patient had hiccups in Group 2 during operation. Average duration of the chest tube was 18.4 hours in Group 1, whereas it was 16.0 hours in Group 2. There were no complication in the two groups and no mortality was observed. All patients were operated uniportally in Group 2. Patients were discharged in an average of 3.4 days in Group 1, while in Group 2 it was 2.0 days. In Group 1, average VAS score in the first postoperative hour was 7.2, 6.0 at the sixth hour, 5.4 in the 12th hour, 3.8 in the 24th hour, 2.8 in the first week. In Group 2 it was 7.6, 6.8, 5.0, 3.8 and 1.6 respectively. Conclusions: Our early results show sedoanalgesia decreases operation time and postoperative pain. Wedge biopsy with sedoanalgesia is a useful and cost-effective approach in patients with ILD to shorten hospital stay and lessen incision pain. Disclosure: No significant relationships.