318MINIMALLY INVASIVE AORTIC VALVE REPLACEMENT WITH THE PERCEVAL S SUTURELESS VALVE: EARLY OUTCOMES AND MID-TERM SURVIVAL FROM TWO EUROPEAN CENTRES

Objectives: The aim of our study was to evaluate early outcomes and mid-term survival in patients undergoing minimally invasive aortic valve replacement (MIAVR) with the Perceval S sutureless valve for severe aortic stenosis. Methods: From March 2010 to March 2013, 281 high-risk patients underwent MIAVR with the Perceval S sutureless valve through either right anterior minithoracotomy (RT group, n = 164) or upper ministernotomy (MS group, n = 117) at two cardiac centres. Results: Overall in-hospital mortality was 0.7% (two patients). Mean cross-clamp and cardiopulmonary bypass times were 59 ± 20 min in the RT group and 40 ± 14 min in the MS group. Postoperative stroke occurred in five patients (1.8%). The incidence of paravalvular leak >1+ and AV block requiring pacemaker implantation was 1.8% (five patients) and 4.2% (12 patients) respectively. No migration occurred and mean postoperative gradient was 13 ± 4 mmHg. At a median follow-up of eight months (interquartile range 4-14), survival was 90% and freedom from reoperation or endocarditis was 99.6%. Conclusions: Minimally invasive aortic valve replacement with the Perceval S sutureless valve in high-risk patients is a safe and reproducible procedure associated with excellent haemodynamic results, postoperative outcomes and mid-term survival.