P3-265SBRT followed by chemotherapy/immunotherapy for stage IVB oropharyngeal cancer with second primary esophageal cancer
Abstract Background We have applied CyberKnife(CK)-based Stereotactic irradiation (SBRT) to patients with primary advanced head and neck cancer(AHNC). The immune checkpoint inhibitor(ICI) was approved for head and neck cancer refractory to cDDP. Synergistic effect of SBRT with ICIs is theoretically...
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| Veröffentlicht in: | Annals of oncology 2019-10, Vol.30 (Supplement_6) |
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| Hauptverfasser: | , |
| Format: | Artikel |
| Sprache: | eng |
| Online-Zugang: | Volltext |
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| Zusammenfassung: | Abstract
Background
We have applied CyberKnife(CK)-based Stereotactic irradiation (SBRT) to patients with primary advanced head and neck cancer(AHNC). The immune checkpoint inhibitor(ICI) was approved for head and neck cancer refractory to cDDP. Synergistic effect of SBRT with ICIs is theoretically expected.
Case
60-year-old male patient complained right huge cervical swelling. Endoscopic finding revealed large ulcerative tumor centered in the right valecula and inferiorly extending into the upper aero-digestive tract. Diagnosis was T4aN3bM0 stage IVB oropharyngeal squamous cell cancer (p16 negative, PDL 1 |
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| ISSN: | 0923-7534 1569-8041 |
| DOI: | 10.1093/annonc/mdz343.142 |