P1-169A novel CSF1R-c-kit dual antagonist eliminates tumor associated macrophage without elevating intratumoral MDSC level

P1-169A novel CSF1R-c-kit dual antagonist eliminates tumor associated macrophage without elevating intratumoral MDSC level

Abstract Results After review of the pre-specified IA, the IDMC recommended full analysis and disclosure of the results. With 256 IDFS events reported, administration of T-DM1 significantly improved IDFS compared with trastuzumab (unstratified HR = 0.50; 95% CI: 0.39 to 0.64; p 

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Veröffentlicht in:Annals of oncology 2019-10, Vol.30 (Supplement_6)
Hauptverfasser: Wang, Ji, Yu, Zhiyong, Qiu, Qingchong, Pang, Wei, Chen, Keke, Chen, Cindy, Liu, Shifeng
Format: Artikel
Sprache:eng
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Zusammenfassung:Abstract Results After review of the pre-specified IA, the IDMC recommended full analysis and disclosure of the results. With 256 IDFS events reported, administration of T-DM1 significantly improved IDFS compared with trastuzumab (unstratified HR = 0.50; 95% CI: 0.39 to 0.64; p 
ISSN:0923-7534
1569-8041
DOI:10.1093/annonc/mdz343.036