1742PDTrilaciclib (T) decreases myelosuppression in extensive-stage small cell lung cancer (ES-SCLC) patients receiving first-line chemotherapy plus atezolizumab

Abstract Background Chemotherapy (chemo)-induced damage of hematopoietic stem and progenitor cells (HSPC) causes multi-lineage myelosuppression. Current supportive therapies are lineage specific and administered after damage has occurred. T, a highly selective, reversible CDK4/6 inhibitor and first-...

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Veröffentlicht in:Annals of oncology 2019-10, Vol.30 (Supplement_5)
Hauptverfasser: Daniel, D, Kuchava, V, Bondarenko, I, Ivashchuk, O, Spigel, D, Dasgupta, A, Reddy, S, Melkadze, T, Jaal, J, Kudaba, I, Hart, L, Matitashvili, A, Koynov, K D, Yang, Z, Wolfe, S G, Malik, R, Morris, S R, Antal, J M, Goldschmidt, J
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Sprache:eng
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