Radiation therapy in the treatment of cervical Cancer: The university of Chicago/Michael reese hospital experience

A retrospective analysis was conducted on 307 patients referred for radiation therapy at The University of Chicago and Michael Reese Hospital between 1971 and 1986. Median follow‐up was 6.4 years. Treatment techniques varied during the time of the study. Actuarial disease‐free survivals were 78%, 64...

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Veröffentlicht in:	Journal of surgical oncology 1990-07, Vol.44 (3), p.157-165
Hauptverfasser:	Rader, Janet S., Haraf, Daniel J., Halpern, Howard J., Rotmensch, Jacob, Spelbring, Danny R., Sutton, Harold, Javaheri, Godratollah, Weichselbaum, Ralph R.
Format:	Artikel
Sprache:	eng
Schlagworte:	Adult BIOLOGICAL EFFECTS BIOLOGICAL RADIATION EFFECTS BODY CARBOXYLIC ACIDS Combined Modality Therapy disease-free survival DISEASES Female FEMALE GENITALS Follow-Up Studies GLOBINS HEMOGLOBIN Hemoglobins - metabolism HETEROCYCLIC ACIDS HETEROCYCLIC COMPOUNDS Humans Hysterectomy Incidence INJURIES lesion size MEDICINE Middle Aged Neoplasm Staging NEOPLASMS NUCLEAR MEDICINE ORGANIC ACIDS ORGANIC COMPOUNDS ORGANIC NITROGEN COMPOUNDS ORGANS PATIENTS PIGMENTS PORPHYRINS PROTEINS RADIATION EFFECTS RADIATION INJURIES Radiation Injuries - epidemiology RADIOLOGY RADIOLOGY AND NUCLEAR MEDICINE RADIOTHERAPY Radiotherapy Dosage Recurrence Retrospective Studies survival SURVIVAL CURVES Survival Rate THERAPY 550603 > Medicine-- External Radiation in Therapy-- (1980-) Uterine Cervical Neoplasms - mortality Uterine Cervical Neoplasms - pathology Uterine Cervical Neoplasms - radiotherapy UTERUS
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Zusammenfassung:	A retrospective analysis was conducted on 307 patients referred for radiation therapy at The University of Chicago and Michael Reese Hospital between 1971 and 1986. Median follow‐up was 6.4 years. Treatment techniques varied during the time of the study. Actuarial disease‐free survivals were 78%, 64%, 55%, 33%, 41%, and 60% for stage IB, IIA, IIB, IIIA, IIIB, and IVA, respectively. Stage, size of the cervical lesion, and hemoglobin level during treatment were prognostic factors. Treatment technique as well as time dose factors were analyzed with respect to survival, failures, and complications.
ISSN:	0022-4790 1096-9098
DOI:	10.1002/jso.2930440307