Free radical activity during development of insulin-dependent diabetes mellitus in the rat

Free radical activity during development of insulin-dependent diabetes mellitus in the rat

Free radical-induced lipid peroxidation was quantified by measuring expired pentane from diabetic prone BB Wistar rats of 45-90 d of age. Insulin-dependent diabetes mellitus was manifest at the age of 71 {plus minus} 8 d. Expired pentane increased from 2.1 {plus minus} 0.7 to 5.0 {plus minus}3.0 pmo...

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Veröffentlicht in:Life sciences (1973) 1991-01, Vol.50:5
Hauptverfasser: Pitkaenen, O.M., Akerblom, H.K., Sariola, H., Andersson, S.M., Martin, J.M., Hallman, M.
Format: Artikel
Sprache:eng
Schlagworte:
ANIMALS
BIOLOGICAL EFFECTS
DIABETES MELLITUS
DISEASES
ENDOCRINE DISEASES
HORMONES
INSULIN
LIPIDS
MAMMALS
METABOLIC DISEASES
METABOLISM
ORGANIC COMPOUNDS
PATHOGENESIS
PEPTIDE HORMONES
PROTEINS
RADIATION, THERMAL, AND OTHER ENVIRON. POLLUTANT EFFECTS ON LIVING ORGS. AND BIOL. MAT
RADICALS
RATS
RODENTS
VERTEBRATES 560300 > Chemicals Metabolism & Toxicology
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Zusammenfassung:Free radical-induced lipid peroxidation was quantified by measuring expired pentane from diabetic prone BB Wistar rats of 45-90 d of age. Insulin-dependent diabetes mellitus was manifest at the age of 71 {plus minus} 8 d. Expired pentane increased from 2.1 {plus minus} 0.7 to 5.0 {plus minus}3.0 pmol/100g/min (p
ISSN:0024-3205
1879-0631