Anomalous Greying Effect in Mice with Higher Doses of X-rays

Exposure of mouse hair follicles to 1200, 1300, and 1400 r of x-rays results in delay of hair growth, precocious melanogenesis, and disruption of melanocyte distribution. The diversity of greying responses obtained with 1100 to 1700 r appears to be due to inactivation of radio-sensitive follicles ra...

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Veröffentlicht in:	Science (American Association for the Advancement of Science) 1962-01, Vol.135 (3498), p.96-97
Hauptverfasser:	Galbraith, Donald B., Chase, Herman B.
Format:	Artikel
Sprache:	eng
Schlagworte:	ANIMAL CELLS Animals Follicles HAIR Hair - radiation effects Hair Follicle Iron Kamacite Melanocytes MICE Microscopes Old Medline PIGMENTS Radiation dosage RADIATION DOSES Radiation Effects RADIOLOGY AND NUCLEAR MEDICINE RADIOSENSITIVITY SKIN Tektites TISSUES X RADIATION X-Rays
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Beschreibung
Zusammenfassung:	Exposure of mouse hair follicles to 1200, 1300, and 1400 r of x-rays results in delay of hair growth, precocious melanogenesis, and disruption of melanocyte distribution. The diversity of greying responses obtained with 1100 to 1700 r appears to be due to inactivation of radio-sensitive follicles rather than to tissue replacement or to displacement of external sheath melanocytes into the hair bulb.
ISSN:	0036-8075 1095-9203
DOI:	10.1126/science.135.3498.96