Indirect Action of X-Radiation on Mammalian Cells

IONIZING radiations may impair the reproductive capacity of cells either by directly altering specific biochemical sites or indirectly by giving rise to free radicals in water which then react chemically with specific sites. In the frozen state the mobility of free radicals is hindered, and conseque...

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Veröffentlicht in:Nature (London) 1962-09, Vol.195 (4845), p.1012-1013
Hauptverfasser: DAWSON, K. B, FIELD, E. O, MADOC JONES, H
Format: Artikel
Sprache:eng
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Zusammenfassung:IONIZING radiations may impair the reproductive capacity of cells either by directly altering specific biochemical sites or indirectly by giving rise to free radicals in water which then react chemically with specific sites. In the frozen state the mobility of free radicals is hindered, and consequently the radio-sensitivity of cells reduced to an extent that depends on the degree to which the indirect mechanism is involved.
ISSN:0028-0836
1476-4687
DOI:10.1038/1951012b0