Probing Mechanical Characteristics of Living Fibroblasts via Atomic Force Microscopy
Atomic force microscopy (AFM) measurements have revealed hardening of intact fibroblasts after treatment with colchicine. The reliability of AFM measurements was confirmed by the identification of cells the lateral response of which to indentation did not disturb the normal force contribution. AFM d...
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Veröffentlicht in: | Technical physics letters 2019-09, Vol.45 (9), p.947-950 |
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creator | Timoshchuk, K. I. Khalisov, M. M. Penniyaynen, V. A. Krylov, B. V. Ankudinov, A. V. |
description | Atomic force microscopy (AFM) measurements have revealed hardening of intact fibroblasts after treatment with colchicine. The reliability of AFM measurements was confirmed by the identification of cells the lateral response of which to indentation did not disturb the normal force contribution. AFM data on the mechanical characteristics of such cells admit an unambiguous interpretation. |
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AFM data on the mechanical characteristics of such cells admit an unambiguous interpretation.</description><identifier>ISSN: 1063-7850</identifier><identifier>EISSN: 1090-6533</identifier><identifier>DOI: 10.1134/S1063785019090293</identifier><language>eng</language><publisher>Moscow: Pleiades Publishing</publisher><subject>ATOMIC AND MOLECULAR PHYSICS ; ATOMIC FORCE MICROSCOPY ; Classical and Continuum Physics ; COLCHICINE ; FIBROBLASTS ; HARDENING ; Indentation ; MATERIALS SCIENCE ; MECHANICAL PROPERTIES ; Microscopes ; Microscopy ; Physics ; Physics and Astronomy ; PROBES ; RELIABILITY</subject><ispartof>Technical physics letters, 2019-09, Vol.45 (9), p.947-950</ispartof><rights>Pleiades Publishing, Ltd. 2019</rights><rights>Copyright Springer Nature B.V. 2019</rights><lds50>peer_reviewed</lds50><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c344t-8d44e336a4515a09ce6fcb7c307a6079ba9be261050ebeac931b85f13a2b3ffb3</citedby><cites>FETCH-LOGICAL-c344t-8d44e336a4515a09ce6fcb7c307a6079ba9be261050ebeac931b85f13a2b3ffb3</cites></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktopdf>$$Uhttps://link.springer.com/content/pdf/10.1134/S1063785019090293$$EPDF$$P50$$Gspringer$$H</linktopdf><linktohtml>$$Uhttps://link.springer.com/10.1134/S1063785019090293$$EHTML$$P50$$Gspringer$$H</linktohtml><link.rule.ids>230,314,780,784,885,27924,27925,41488,42557,51319</link.rule.ids><backlink>$$Uhttps://www.osti.gov/biblio/22929171$$D View this record in Osti.gov$$Hfree_for_read</backlink></links><search><creatorcontrib>Timoshchuk, K. 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AFM data on the mechanical characteristics of such cells admit an unambiguous interpretation.</description><subject>ATOMIC AND MOLECULAR PHYSICS</subject><subject>ATOMIC FORCE MICROSCOPY</subject><subject>Classical and Continuum Physics</subject><subject>COLCHICINE</subject><subject>FIBROBLASTS</subject><subject>HARDENING</subject><subject>Indentation</subject><subject>MATERIALS SCIENCE</subject><subject>MECHANICAL PROPERTIES</subject><subject>Microscopes</subject><subject>Microscopy</subject><subject>Physics</subject><subject>Physics and Astronomy</subject><subject>PROBES</subject><subject>RELIABILITY</subject><issn>1063-7850</issn><issn>1090-6533</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2019</creationdate><recordtype>article</recordtype><recordid>eNp1kE9LAzEQxYMoWP98AG8Bz6uTZDe7OZZiVagoqOeQjNk2pd3UJC3027tLhR7E0zyY33vMPEJuGNwxJsr7dwZS1E0FTIECrsQJGbFeFbIS4nTQUhTD_pxcpLQEgIZXakQ-3mKwvpvTF4cL03k0KzpZmGgwu-hT9phoaOnM7wZo6m2Pr0zKie68oeMc1h7pNER09MVjDAnDZn9FzlqzSu76d16Sz-nDx-SpmL0-Pk_GswJFWeai-SpLJ4Q0ZcUqAwqdbNHWKKA2EmpljbKOSwYVOOsMKsFsU7VMGG5F21pxSW4PuaE_VCf0uX8CQ9c5zJpzxRWr2ZHaxPC9dSnrZdjGrj9McwHAeS0b1VPsQA1PpOhavYl-beJeM9BDxfpPxb2HHzypZ7u5i8fk_00_IE583w</recordid><startdate>20190901</startdate><enddate>20190901</enddate><creator>Timoshchuk, K. 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The reliability of AFM measurements was confirmed by the identification of cells the lateral response of which to indentation did not disturb the normal force contribution. AFM data on the mechanical characteristics of such cells admit an unambiguous interpretation.</abstract><cop>Moscow</cop><pub>Pleiades Publishing</pub><doi>10.1134/S1063785019090293</doi><tpages>4</tpages></addata></record> |
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subjects | ATOMIC AND MOLECULAR PHYSICS ATOMIC FORCE MICROSCOPY Classical and Continuum Physics COLCHICINE FIBROBLASTS HARDENING Indentation MATERIALS SCIENCE MECHANICAL PROPERTIES Microscopes Microscopy Physics Physics and Astronomy PROBES RELIABILITY |
title | Probing Mechanical Characteristics of Living Fibroblasts via Atomic Force Microscopy |
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