Synthesis of 1,1´-[methylenebis(oxy)]bis[3-alkyl-3-(2-haloethyl)triaz-1-ene 2-oxides]

A method for the synthesis of promising nitric oxide donors in living organisms, 1,1´-[methylenebis(oxy)]bis[3-alkyl-3-(2-haloethyl)triaz-1-ene 2-oxides] was elaborated. The method involved replacement of hydroxy groups of the corresponding 1,1´-[methylenebis(oxy)]bis[3-alkyl-3-(2-hydroxyethyl)triaz...

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Veröffentlicht in:	Russian chemical bulletin 2017-07, Vol.66 (7), p.1234-1239
Hauptverfasser:	Pokhvisneva, G. V., Ternikova, T. V., Smirnov, G. A., Gordeev, P. B., Nikitin, S. V., Luk´yanov, O. A.
Format:	Artikel
Sprache:	eng
Schlagworte:	ALKYLATION ATOMS BROMINATION Chemistry Chemistry and Materials Science Chemistry/Food Science CHLORINATION Full Articles HALOGENS Inorganic Chemistry INORGANIC, ORGANIC, PHYSICAL AND ANALYTICAL CHEMISTRY IODINATION NITRIC OXIDE Organic Chemistry SYNTHESIS
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Beschreibung
Zusammenfassung:	A method for the synthesis of promising nitric oxide donors in living organisms, 1,1´-[methylenebis(oxy)]bis[3-alkyl-3-(2-haloethyl)triaz-1-ene 2-oxides] was elaborated. The method involved replacement of hydroxy groups of the corresponding 1,1´-[methylenebis(oxy)]bis[3-alkyl-3-(2-hydroxyethyl)triaz-1-ene 2-oxides] by halogen atoms and, in some cases, the exchange of one halogen atom for another.
ISSN:	1066-5285 1573-9171
DOI:	10.1007/s11172-017-1878-5