Development of Anti-bacterial PVA/Starch Based Hydrogel Membrane for Wound Dressing
Wound infection is the primary challenge in the wound care management. To facilitate patients, the health care sector is trying to use the modern technology in the field of wound management. Various cellular processes and biological environments are intertwined in the process of wound repair. The co...
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| Veröffentlicht in: | Journal of polymers and the environment 2018-01, Vol.26 (1), p.235-243 |
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| creator | Hassan, Awais Niazi, Muhammad Bilal Khan Hussain, Arshad Farrukh, Sarah Ahmad, Tahir |
| description | Wound infection is the primary challenge in the wound care management. To facilitate patients, the health care sector is trying to use the modern technology in the field of wound management. Various cellular processes and biological environments are intertwined in the process of wound repair. The compulsion for the modern dressing is not only to cover the wound but also to facilitate the healing rate of wound. In this research, the hydrogel membranes were prepared by crosslinking poly vinyl alcohol (PVA) with starch by using glutaraldehyde. Turmeric was added as an anti-bacterial agent. 0.5 g of turmeric showed the highest anti-bacterial activity among different turmeric contents used. For physical and mechanical characterization, the hydrogel membrane without turmeric (neat hydrogel) and 0.5 g were selected. FTIR of both hydrogel membranes confirmed the presence of free hydroxyl groups. Moreover, hydrogel membrane containing turmeric resulted stronger hydrogen bond interaction. Mechanical analysis of hydrogel membrane revealed sufficient strength to be used as wound dressing. The SEM images evolved that both hydrogel membranes were dense in nature. The swelling behavior values were greater than 100% for both hydrogel membranes. The water vapor transmission rate for 0.5 g turmeric hydrogel membrane was 52.85 g/m
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| doi_str_mv | 10.1007/s10924-017-0944-2 |
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2
h.</description><identifier>ISSN: 1566-2543</identifier><identifier>EISSN: 1572-8919</identifier><identifier>EISSN: 1572-8900</identifier><identifier>DOI: 10.1007/s10924-017-0944-2</identifier><language>eng</language><publisher>New York: Springer US</publisher><subject>60 APPLIED LIFE SCIENCES ; Alcohols ; antibacterial properties ; antibiotics ; ANTIMICROBIAL AGENTS ; Bacteria ; Biological activity ; BIOLOGICAL REPAIR ; Chemistry ; Chemistry and Materials Science ; CROSS-LINKING ; Crosslinking ; Environmental Chemistry ; Environmental Engineering/Biotechnology ; Fourier transform infrared spectroscopy ; FOURIER TRANSFORM SPECTROMETERS ; Glutaraldehyde ; HEALING ; health services ; HYDROGELS ; HYDROGEN ; hydrogen bonding ; Hydrogen bonds ; HYDROXIDES ; Hydroxyl groups ; Industrial Chemistry/Chemical Engineering ; MATERIALS SCIENCE ; Mechanical analysis ; Mechanical properties ; Membrane separation ; MEMBRANES ; moieties ; Original Paper ; PATIENTS ; Polymer Sciences ; polyvinyl alcohol ; PVA ; RADIATION CHEMISTRY, RADIOCHEMISTRY AND NUCLEAR CHEMISTRY ; SCANNING ELECTRON MICROSCOPY ; STARCH ; SWELLING ; turmeric ; WATER VAPOR ; Wound healing ; Wound infection ; wound treatment ; WOUNDS</subject><ispartof>Journal of polymers and the environment, 2018-01, Vol.26 (1), p.235-243</ispartof><rights>Springer Science+Business Media New York 2017</rights><rights>Journal of Polymers and the Environment is a copyright of Springer, (2017). All Rights Reserved.</rights><lds50>peer_reviewed</lds50><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c377t-50e41b99e553173746e3563ef8bb9ba8098a5ae96396d224c925a2616ba60b43</citedby><cites>FETCH-LOGICAL-c377t-50e41b99e553173746e3563ef8bb9ba8098a5ae96396d224c925a2616ba60b43</cites></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktopdf>$$Uhttps://link.springer.com/content/pdf/10.1007/s10924-017-0944-2$$EPDF$$P50$$Gspringer$$H</linktopdf><linktohtml>$$Uhttps://link.springer.com/10.1007/s10924-017-0944-2$$EHTML$$P50$$Gspringer$$H</linktohtml><link.rule.ids>230,314,776,780,881,27901,27902,41464,42533,51294</link.rule.ids><backlink>$$Uhttps://www.osti.gov/biblio/22788301$$D View this record in Osti.gov$$Hfree_for_read</backlink></links><search><creatorcontrib>Hassan, Awais</creatorcontrib><creatorcontrib>Niazi, Muhammad Bilal Khan</creatorcontrib><creatorcontrib>Hussain, Arshad</creatorcontrib><creatorcontrib>Farrukh, Sarah</creatorcontrib><creatorcontrib>Ahmad, Tahir</creatorcontrib><title>Development of Anti-bacterial PVA/Starch Based Hydrogel Membrane for Wound Dressing</title><title>Journal of polymers and the environment</title><addtitle>J Polym Environ</addtitle><description>Wound infection is the primary challenge in the wound care management. To facilitate patients, the health care sector is trying to use the modern technology in the field of wound management. Various cellular processes and biological environments are intertwined in the process of wound repair. The compulsion for the modern dressing is not only to cover the wound but also to facilitate the healing rate of wound. In this research, the hydrogel membranes were prepared by crosslinking poly vinyl alcohol (PVA) with starch by using glutaraldehyde. Turmeric was added as an anti-bacterial agent. 0.5 g of turmeric showed the highest anti-bacterial activity among different turmeric contents used. For physical and mechanical characterization, the hydrogel membrane without turmeric (neat hydrogel) and 0.5 g were selected. FTIR of both hydrogel membranes confirmed the presence of free hydroxyl groups. Moreover, hydrogel membrane containing turmeric resulted stronger hydrogen bond interaction. Mechanical analysis of hydrogel membrane revealed sufficient strength to be used as wound dressing. The SEM images evolved that both hydrogel membranes were dense in nature. The swelling behavior values were greater than 100% for both hydrogel membranes. The water vapor transmission rate for 0.5 g turmeric hydrogel membrane was 52.85 g/m
2
h.</description><subject>60 APPLIED LIFE SCIENCES</subject><subject>Alcohols</subject><subject>antibacterial properties</subject><subject>antibiotics</subject><subject>ANTIMICROBIAL AGENTS</subject><subject>Bacteria</subject><subject>Biological activity</subject><subject>BIOLOGICAL REPAIR</subject><subject>Chemistry</subject><subject>Chemistry and Materials Science</subject><subject>CROSS-LINKING</subject><subject>Crosslinking</subject><subject>Environmental Chemistry</subject><subject>Environmental Engineering/Biotechnology</subject><subject>Fourier transform infrared spectroscopy</subject><subject>FOURIER TRANSFORM SPECTROMETERS</subject><subject>Glutaraldehyde</subject><subject>HEALING</subject><subject>health services</subject><subject>HYDROGELS</subject><subject>HYDROGEN</subject><subject>hydrogen bonding</subject><subject>Hydrogen bonds</subject><subject>HYDROXIDES</subject><subject>Hydroxyl groups</subject><subject>Industrial Chemistry/Chemical Engineering</subject><subject>MATERIALS SCIENCE</subject><subject>Mechanical analysis</subject><subject>Mechanical properties</subject><subject>Membrane separation</subject><subject>MEMBRANES</subject><subject>moieties</subject><subject>Original Paper</subject><subject>PATIENTS</subject><subject>Polymer Sciences</subject><subject>polyvinyl alcohol</subject><subject>PVA</subject><subject>RADIATION CHEMISTRY, RADIOCHEMISTRY AND NUCLEAR CHEMISTRY</subject><subject>SCANNING ELECTRON MICROSCOPY</subject><subject>STARCH</subject><subject>SWELLING</subject><subject>turmeric</subject><subject>WATER VAPOR</subject><subject>Wound healing</subject><subject>Wound infection</subject><subject>wound treatment</subject><subject>WOUNDS</subject><issn>1566-2543</issn><issn>1572-8919</issn><issn>1572-8900</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2018</creationdate><recordtype>article</recordtype><sourceid>BENPR</sourceid><recordid>eNp1kU1LHEEQhocQIcb4A3Jr8OKlY3_31HGjRgUlgmKOTU9vzToy27129wr-e2cZCV48VR2e56WKt2l-cvaLM2ZPCmcgFGXcUgZKUfGl2efaCtoCh6-73RgqtJLfmu-lPDHGYPL2m7szfMExbdYYK0k9WcQ60M6HinnwI7l9WJzcVZ_DI_ntCy7J5esypxWO5AbXXfYRSZ8y-Ze2cUnOMpYyxNWPZq_3Y8HD93nQ3P85vz-9pNd_L65OF9c0SGsr1QwV7wBQa8mttMqg1EZi33YddL5l0HrtEYwEsxRCBRDaC8NN5w3rlDxojubYVOrgShgqhseQYsRQnRC2bSXjE3U8U5ucnrdYqlsPJeA4TrenbXGCtYpJZeFD4H_0KW1znF5wHEBq0MB3gXymQk6lZOzdJg9rn18dZ27XhZu7cFMXbteFE5MjZqdMbFxh_pD8qfQGoUKJFw</recordid><startdate>20180101</startdate><enddate>20180101</enddate><creator>Hassan, Awais</creator><creator>Niazi, Muhammad Bilal Khan</creator><creator>Hussain, Arshad</creator><creator>Farrukh, Sarah</creator><creator>Ahmad, Tahir</creator><general>Springer 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Niazi, Muhammad Bilal Khan ; Hussain, Arshad ; Farrukh, Sarah ; Ahmad, Tahir</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c377t-50e41b99e553173746e3563ef8bb9ba8098a5ae96396d224c925a2616ba60b43</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2018</creationdate><topic>60 APPLIED LIFE SCIENCES</topic><topic>Alcohols</topic><topic>antibacterial properties</topic><topic>antibiotics</topic><topic>ANTIMICROBIAL AGENTS</topic><topic>Bacteria</topic><topic>Biological activity</topic><topic>BIOLOGICAL REPAIR</topic><topic>Chemistry</topic><topic>Chemistry and Materials Science</topic><topic>CROSS-LINKING</topic><topic>Crosslinking</topic><topic>Environmental Chemistry</topic><topic>Environmental Engineering/Biotechnology</topic><topic>Fourier transform infrared spectroscopy</topic><topic>FOURIER TRANSFORM SPECTROMETERS</topic><topic>Glutaraldehyde</topic><topic>HEALING</topic><topic>health services</topic><topic>HYDROGELS</topic><topic>HYDROGEN</topic><topic>hydrogen bonding</topic><topic>Hydrogen bonds</topic><topic>HYDROXIDES</topic><topic>Hydroxyl groups</topic><topic>Industrial Chemistry/Chemical Engineering</topic><topic>MATERIALS SCIENCE</topic><topic>Mechanical analysis</topic><topic>Mechanical properties</topic><topic>Membrane separation</topic><topic>MEMBRANES</topic><topic>moieties</topic><topic>Original Paper</topic><topic>PATIENTS</topic><topic>Polymer Sciences</topic><topic>polyvinyl alcohol</topic><topic>PVA</topic><topic>RADIATION CHEMISTRY, RADIOCHEMISTRY AND NUCLEAR CHEMISTRY</topic><topic>SCANNING ELECTRON MICROSCOPY</topic><topic>STARCH</topic><topic>SWELLING</topic><topic>turmeric</topic><topic>WATER VAPOR</topic><topic>Wound healing</topic><topic>Wound infection</topic><topic>wound treatment</topic><topic>WOUNDS</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Hassan, 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Environ</stitle><date>2018-01-01</date><risdate>2018</risdate><volume>26</volume><issue>1</issue><spage>235</spage><epage>243</epage><pages>235-243</pages><issn>1566-2543</issn><eissn>1572-8919</eissn><eissn>1572-8900</eissn><abstract>Wound infection is the primary challenge in the wound care management. To facilitate patients, the health care sector is trying to use the modern technology in the field of wound management. Various cellular processes and biological environments are intertwined in the process of wound repair. The compulsion for the modern dressing is not only to cover the wound but also to facilitate the healing rate of wound. In this research, the hydrogel membranes were prepared by crosslinking poly vinyl alcohol (PVA) with starch by using glutaraldehyde. Turmeric was added as an anti-bacterial agent. 0.5 g of turmeric showed the highest anti-bacterial activity among different turmeric contents used. For physical and mechanical characterization, the hydrogel membrane without turmeric (neat hydrogel) and 0.5 g were selected. FTIR of both hydrogel membranes confirmed the presence of free hydroxyl groups. Moreover, hydrogel membrane containing turmeric resulted stronger hydrogen bond interaction. Mechanical analysis of hydrogel membrane revealed sufficient strength to be used as wound dressing. The SEM images evolved that both hydrogel membranes were dense in nature. The swelling behavior values were greater than 100% for both hydrogel membranes. The water vapor transmission rate for 0.5 g turmeric hydrogel membrane was 52.85 g/m
2
h.</abstract><cop>New York</cop><pub>Springer US</pub><doi>10.1007/s10924-017-0944-2</doi><tpages>9</tpages></addata></record> |
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| subjects | 60 APPLIED LIFE SCIENCES Alcohols antibacterial properties antibiotics ANTIMICROBIAL AGENTS Bacteria Biological activity BIOLOGICAL REPAIR Chemistry Chemistry and Materials Science CROSS-LINKING Crosslinking Environmental Chemistry Environmental Engineering/Biotechnology Fourier transform infrared spectroscopy FOURIER TRANSFORM SPECTROMETERS Glutaraldehyde HEALING health services HYDROGELS HYDROGEN hydrogen bonding Hydrogen bonds HYDROXIDES Hydroxyl groups Industrial Chemistry/Chemical Engineering MATERIALS SCIENCE Mechanical analysis Mechanical properties Membrane separation MEMBRANES moieties Original Paper PATIENTS Polymer Sciences polyvinyl alcohol PVA RADIATION CHEMISTRY, RADIOCHEMISTRY AND NUCLEAR CHEMISTRY SCANNING ELECTRON MICROSCOPY STARCH SWELLING turmeric WATER VAPOR Wound healing Wound infection wound treatment WOUNDS |
| title | Development of Anti-bacterial PVA/Starch Based Hydrogel Membrane for Wound Dressing |
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