Impact of Intrafraction and Residual Interfraction Effect on Prostate Proton Pencil Beam Scanning

Impact of Intrafraction and Residual Interfraction Effect on Prostate Proton Pencil Beam Scanning

Purpose To quantitatively evaluate the impact of interplay effect and plan robustness associated with intrafraction and residual interfraction prostate motion for pencil beam scanning proton therapy. Methods and Materials Ten prostate cancer patients with weekly verification CTs underwent pencil bea...

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Veröffentlicht in:International journal of radiation oncology, biology, physics biology, physics, 2014-12, Vol.90 (5), p.1186-1194
Hauptverfasser: Tang, Shikui, PhD, Deville, Curtiland, MD, Tochner, Zelig, MD, Wang, Ken Kang-Hsin, PhD, McDonough, James, PhD, Vapiwala, Neha, MD, Both, Stefan, PhD
Format: Artikel
Sprache:eng
Schlagworte:
Anatomic Landmarks
CAT SCANNING
Dose Fractionation
Fiducial Markers
Hematology, Oncology and Palliative Medicine
Humans
Male
Movement
NEOPLASMS
Organs at Risk - diagnostic imaging
PATIENTS
PLANNING
PROSTATE
Prostatic Neoplasms - diagnostic imaging
Prostatic Neoplasms - radiotherapy
PROTON BEAMS
Proton Therapy - methods
RADIATION DOSES
Radiology
RADIOLOGY AND NUCLEAR MEDICINE
RADIOTHERAPY
Radiotherapy Planning, Computer-Assisted - methods
Radiotherapy, Intensity-Modulated - methods
RECTUM
Rectum - diagnostic imaging
Rectum - radiation effects
Relative Biological Effectiveness
Tomography, X-Ray Computed
Urinary Bladder - diagnostic imaging
Urinary Bladder - radiation effects
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Zusammenfassung:Purpose To quantitatively evaluate the impact of interplay effect and plan robustness associated with intrafraction and residual interfraction prostate motion for pencil beam scanning proton therapy. Methods and Materials Ten prostate cancer patients with weekly verification CTs underwent pencil beam scanning with the bilateral single-field uniform dose (SFUD) modality. A typical field had 10-15 energy layers and 500-1000 spots. According to their treatment logs, each layer delivery time was
ISSN:0360-3016
1879-355X
DOI:10.1016/j.ijrobp.2014.08.015