Recovery from diabetes in neonatal mice after a low-dose streptozotocin treatment

► We monitored long-term beta cell regeneration in neonatal mice treated with low dose STZ. ► Low-dose STZ neonatal female mice recovered blood glucose in 150days. ► Glucose intolerance of the STZ treated mice significantly improved in 150days. Administration of streptozotocin (STZ) induces destruct...

Ausführliche Beschreibung

Gespeichert in:

Bibliographische Detailangaben
Veröffentlicht in:	Biochemical and biophysical research communications 2013-01, Vol.430 (3), p.1103-1108
Hauptverfasser:	Kataoka, Masateru, Kawamuro, Yuki, Shiraki, Nobuaki, Miki, Rika, Sakano, Daisuke, Yoshida, Tetsu, Yasukawa, Takanori, Kume, Kazuhiko, Kume, Shoen
Format:	Artikel
Sprache:	eng
Schlagworte:	60 APPLIED LIFE SCIENCES Animals Animals, Newborn Beta-cell BLOOD Blood Glucose - metabolism Cell Proliferation Diabetes Diabetes Mellitus, Experimental - metabolism Diabetes Mellitus, Experimental - pathology Diabetes Mellitus, Type 1 - metabolism Diabetes Mellitus, Type 1 - pathology Dose-Response Relationship, Drug Female GLUCOSE HYPERGLYCEMIA Hyperglycemia - metabolism Hyperglycemia - pathology INSULIN Insulin-Secreting Cells - drug effects Insulin-Secreting Cells - pathology Insulin-Secreting Cells - physiology MICE Mice, Inbred ICR PANCREAS RATS Regeneration STREPTOZOCIN Streptozocin - administration & dosage Streptozocin - toxicity Streptozotocin TOLERANCE
Online-Zugang:	Volltext
Tags:	Tag hinzufügen Keine Tags, Fügen Sie den ersten Tag hinzu!

Schreiben Sie den ersten Kommentar!