Impact of Pretreatment Body Mass Index on Patients With Head-and-Neck Cancer Treated With Radiation

Purpose To investigate the association of pretreatment body mass index (preT BMI) with outcomes of head-and-neck cancer in patients treated with radiotherapy (RT). Methods and Materials All 1,562 patients diagnosed with head-and-neck cancer and treated with curative-intent RT to a dose of 60 Gy or h...

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Veröffentlicht in:	International journal of radiation oncology, biology, physics biology, physics, 2012-05, Vol.83 (1), p.e93-e100
Hauptverfasser:	Pai, Ping-Ching, M.D, Chuang, Chi-Cheng, M.D, Tseng, Chen-Kan, M.D, Tsang, Ngan-Ming, D.Sc, Chang, Kai-Ping, M.D, Yen, Tzu-Chen, M.D., Ph.D, Liao, Chun-Ta, M.D, Hong, Ji-Hong, M.D., Ph.D, Chang, Joseph Tung-Chieh, M.D
Format:	Artikel
Sprache:	eng
Schlagworte:	Adult Aged Aged, 80 and over Body Mass Index Body weight loss Educational Status Female HEAD Head and Neck Neoplasms - mortality Head and Neck Neoplasms - physiopathology Head and Neck Neoplasms - radiotherapy Head-and-neck cancer Hematology, Oncology and Palliative Medicine Humans Hypopharyngeal Neoplasms - mortality Hypopharyngeal Neoplasms - physiopathology Hypopharyngeal Neoplasms - radiotherapy Laryngeal Neoplasms - mortality Laryngeal Neoplasms - physiopathology Laryngeal Neoplasms - radiotherapy Male METASTASES Middle Aged Mouth Neoplasms - mortality Mouth Neoplasms - physiopathology Mouth Neoplasms - radiotherapy NECK NEOPLASMS Nutritional Status - physiology Obesity - mortality Oropharyngeal Neoplasms - mortality Oropharyngeal Neoplasms - physiopathology Oropharyngeal Neoplasms - radiotherapy PATIENTS Prognosis RADIATION DOSES Radiology RADIOLOGY AND NUCLEAR MEDICINE RADIOTHERAPY Radiotherapy Dosage Retrospective Studies Survival Analysis Taiwan Thinness - mortality Weight Loss Young Adult
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Zusammenfassung:	Purpose To investigate the association of pretreatment body mass index (preT BMI) with outcomes of head-and-neck cancer in patients treated with radiotherapy (RT). Methods and Materials All 1,562 patients diagnosed with head-and-neck cancer and treated with curative-intent RT to a dose of 60 Gy or higher were retrospectively studied. Body weight was measured both at entry and at the end of RT. Cancer-specific survival (CSS), overall survival (OS), locoregional control (LRC), and distant metastasis (DM) were analyzed by preT BMI (
ISSN:	0360-3016 1879-355X
DOI:	10.1016/j.ijrobp.2011.11.071